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Rapid Asparagine Depletion as a Possible Risk Marker for Pancreatitis in Children with Acute Lymphoblastic Leukemia Under Treatment with L-Asparaginase- Case Report from Five Patients

Author

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  • Ismael Lares-Asseff

    (Academia de Genómica, Instituto Politécnico Nacional, CIIDIR-Unidad Durango, México)

Abstract

We will be describing our experience with five patients diagnosed with acute lymphoblastic leukemia (ALL), who developed L-Asparaginase (L-Asp)-induced pancreatitis during their remission induction stage. The patients were treated, at the State Cancer Center of Durango, Mexico (CECAN-Durango) since December 2021, along with a group of 30 pediatric patients (in the remission induction phase of their treatment) who did not develop pancreatitis. All patients were diagnosed with (ALL) according to criteria from the French American-British Hematology Association (FAB). Once diagnosed, patients were treated according to the St. Jude Total XV protocol.

Suggested Citation

  • Ismael Lares-Asseff, 2023. "Rapid Asparagine Depletion as a Possible Risk Marker for Pancreatitis in Children with Acute Lymphoblastic Leukemia Under Treatment with L-Asparaginase- Case Report from Five Patients," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 50(4), pages 41929-41934, May.
    • Handle: RePEc:abf:journl:v:50:y:2023:i:4:p:41929-41934
    DOI: 10.26717/BJSTR.2023.50.007993
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