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Diagnostic Value of Galectin-3 in Benign Thyroid Neoplasm vs. Differentiated Thyroid Carcinoma

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  • Matthias Kapischke

    (Klinikum Guetersloh, Department of Surgery, Germany)

Abstract

Discrimination between malignant nodules and their precursors – and interim forms remain a diagnostic dilemma; specially to avoid over therapy. Even though Galectin-3 (Gal-3) expression is a marker investigated quite often, this marker is the focus of this manuscript to compare risk constellations in subgroups. In total 283 specimens were investigated regarding their Galectin-3 expression by applying immunohistochemistry. Subgroups were performed (cPTC n=28, FVPTC n= 44, FTC n=51, FA n= 85 and PH n=14) and compared in the risk constella-tions. Sensitivity and specificity of Galectin-3 expression were checked against each other

Suggested Citation

  • Matthias Kapischke, 2023. "Diagnostic Value of Galectin-3 in Benign Thyroid Neoplasm vs. Differentiated Thyroid Carcinoma," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 50(3), pages 41750-41756, May.
    • Handle: RePEc:abf:journl:v:50:y:2023:i:3:p:41750-41756
    DOI: 10.26717/BJSTR.2023.50.007967
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