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Atypical Presentation of Sarcoidosis with Retroperitoneal Fibrosis, Non-Caseating Granulomatous Perinephric Lesion and Obstructive Uropathy

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  • Ramchandani Santosh

    (Lehigh Valley Hospital, Allentown, USA)

Abstract

A 66 year old female was admitted to the hospital with acute renal failure, hyperkalemia, and anemia. Etiology of her acute renal failure was obscure, and all serologic studies were negative. A kidney biopsy was performed shows interstitial infiltration noncaseating granulomas. CT scan abdomen revealed bilateral kidney enlargement and retroperitoneal fibrosis (RPF). Perinephric tissue also demonstrated dense fibrosis, inflammation and noncaseating granulomas. Treatment was initiated with 80mg of prednisone and bilateral ureteral stents were inserted because of fullness of collecting system seen on CT scan. Over 2 weeks, renal function improved towards normal. Kidney and retroperitoneal findings highly suggested renal sarcoidosis.

Suggested Citation

  • Ramchandani Santosh, 2023. "Atypical Presentation of Sarcoidosis with Retroperitoneal Fibrosis, Non-Caseating Granulomatous Perinephric Lesion and Obstructive Uropathy," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 50(3), pages 41635-41639, May.
  • Handle: RePEc:abf:journl:v:50:y:2023:i:3:p:41635-41639
    DOI: 10.26717/BJSTR.2023.50.007948
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