IDEAS home Printed from https://ideas.repec.org/a/abf/journl/v50y2023i1p41270-41278.html
   My bibliography  Save this article

The Place of Osteoimmunology in the Pathogenesis of Rheumatic Joint and Bone Diseases

Author

Listed:
  • Momcheva I

    (University Multiprofile Hospital for Active Treatment Burgas, Bulgaria)

Abstract

The bone and immune cells all share the same microenvironment, interact with each other, share common signaling pathways, collaborate, performing the functions of an “osteoimmune system†. The same cytokines may have different and often opposite effects depending on the specific environment in which they function, the maturation stage of the target cells and/or the influence of other cytokines. Through osteoimmunology, the intimate mechanisms in the pathogenesis of many rheumatological diseases such as Rheumatoid arthritis, axSpA, autoinflammatory diseases, osteonecrosis, osteoarthrosis, osteoporosis are clarified. Osteoimmunology is a conceptual framework for decoding the complex language through which the immune system and bone communicate. This review summarizes the data accumulated to date on the interactions between the immune and bone systems of the human organism and reveals the bidirectionality of these interactions and their role in the pathogenesis of rheumatic joint and bone diseases.

Suggested Citation

  • Momcheva I, 2023. "The Place of Osteoimmunology in the Pathogenesis of Rheumatic Joint and Bone Diseases," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 50(1), pages 41270-41278, April.
    • Handle: RePEc:abf:journl:v:50:y:2023:i:1:p:41270-41278
    DOI: 10.26717/BJSTR.2023.50.007894
    as

    Download full text from publisher

    File URL: https://biomedres.us/pdfs/BJSTR.MS.ID.007894.pdf
    Download Restriction: no
    File URL: https://biomedres.us/fulltexts/BJSTR.MS.ID.007894.php
    Download Restriction: no
    File URL: https://libkey.io/10.26717/BJSTR.2023.50.007894?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:abf:journl:v:50:y:2023:i:1:p:41270-41278. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Angela Roy (email available below). General contact details of provider: .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.