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A Case of Pseudopheochromocytoma- Quetiapine Induction of Norepinephine

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  • T Patrick Jensen

    (Medical Director of Consult and Liaison Psychiatry Service and Senior Behavioral Unit, Covenant Health, USA)

Abstract

An acutely altered elderly female presented following orthopedic repair. She was afebrile, normotensive, but tachycardic. Once declared medically stable, she was transferred to a geropsychiatric facility for stabilization of acute psychosis. Her psychosis remained refractory to treatment, and she was noted to have an elevated ionized calcium. Plasma metanephrines were evaluated, followed by confirmatory urinary metanephrines. Both were significantly elevated. Negative imaging following this laboratory workup prompted consideration of possible tertiary causes. It was determined that the patient was likely experiencing a phenomenon known as Pseudopheochromocytoma, induced by Seroquel, of which she was on the maximum recommended dose. Once Seroquel was discontinued, the patient’s autonomic instability stabilized. Although a pheochromocytoma was not completely excluded by a PET scan in this case, its existence was unlikely, especially given autonomic improvement following Seroquel taper and discontinuation.

Suggested Citation

  • T Patrick Jensen, 2023. "A Case of Pseudopheochromocytoma- Quetiapine Induction of Norepinephine," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 49(4), pages 40934-40940, April.
  • Handle: RePEc:abf:journl:v:49:y:2023:i:4:p:40934-40940
    DOI: 10.26717/BJSTR.2023.49.007843
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