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Allograft Model for Disease Monitoring and Therapeutics

Author

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  • Sandhiya V

    (Assistant professor, Department of pharmaceutics, C.L.baid metha college of pharmacy, India)

Abstract

Ehrlich ascites carcinoma (EAC), one of the most prevalent malignancies, is extremely important for modelling. EAC, also known as an undifferentiated carcinoma, is initially hyperdiploid, highly transplantable, never regresses, proliferates quickly, has a shorter life span, and is completely malignant. It also lacks the tumorspecific transplantation antigen (TSTA). Often, the proliferation rate of these tumours develops gradually as the virulence of the tumour increases via repeated passages. However, the differentiation gradually vanishes as the cells acquire free growth control systems, increase their hetero-transplantability, and ultimately take on the appearance of ascites. Due to its undifferentiated nature and quick rate of proliferation, EAC resembles human cancers, which are the most susceptible to treatment. At this stage, the utilization of natural sources as an alternative cancer therapy is regarded to have considerable value for cancer control and the destruction of cancer programmes because the optimal medicine has been focused on and has been shown to be inefficient or minimally beneficial for normal cells.

Suggested Citation

  • Sandhiya V, 2023. "Allograft Model for Disease Monitoring and Therapeutics," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 49(3), pages 40634-40637, March.
    • Handle: RePEc:abf:journl:v:49:y:2023:i:3:p:40634-40637
    DOI: 10.26717/BJSTR.2023.49.007796
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