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Clinical Trial to Evaluate if Balenine, A Major Component of Whale Meat Extract, Improves Cognitive Function in Subjects with Symptoms of Increasing Forgetfulness

Author

Listed:
  • Seiji Shioda

    (Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Shonan University of Medical Sciences, Japan)

  • Fumiko Takenoya

    (Department of Sports Sciences, School of Pharmacy, Hoshi University, Japan)

Abstract

Balenine (beta-alanyl-N tau-methyl histidine), an imidazole dipeptide reported to have antioxidant and anti-fatigue effects in animal models and humans, is present in abundant amounts in whale meat. Previously, we reported that long-term consumption of whale meat extracts containing balenine improve cognitive function in a mouse model of Alzheimer’s disease. To test whether this cognition-improving effect of balenine can also be observed in humans, we conducted a double-blind clinical trial in subjects with symptoms of increasing forgetfulness.

Suggested Citation

  • Seiji Shioda & Fumiko Takenoya, 2023. "Clinical Trial to Evaluate if Balenine, A Major Component of Whale Meat Extract, Improves Cognitive Function in Subjects with Symptoms of Increasing Forgetfulness," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 49(2), pages 40391-40400, March.
    • Handle: RePEc:abf:journl:v:49:y:2023:i:2:p:40391-40400
    DOI: 10.26717/BJSTR.2023.49.007766
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