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Preparation and Characterization of Responsive Terpolymer Nano Carrier for Alzheimer’s Treatment

Author

Listed:
  • Fahima M Helaly

    (Polymers and Pigments Department, National Research Centre, Egypt)

  • Sally A Abou Taleb

    (Pharmacutical Technology Department, National Research Centre, Egypt)

  • Bassant M Ibrahim

    (Pharmacology Department, National Research Centre, Egypt)

  • Reda M Mourad

    (Polymers and Pigments Department, National Research Centre, Egypt)

  • Eman AboBakr Ali

    (Polymers and Pigments Department, National Research Centre, Egypt)

Abstract

This work aims to prepare the promising responsive terpolymer nanoparticles for targeting and sustained release of natural therapeutic Curcumin (Curm) and/or active agents Donepezil hydrochloride (DH). N-isopropyl acrylamide - 2 (dimethylamino) ethyl methacrylate – butyl methacrylate (B5) and N-isopropyl acrylamide - 2 (dimethylamino) ethyl methacrylate – styrene (S5) terpolymers were successfully synthesized and characterized by spectral analysis.

Suggested Citation

  • Fahima M Helaly & Sally A Abou Taleb & Bassant M Ibrahim & Reda M Mourad & Eman AboBakr Ali, 2023. "Preparation and Characterization of Responsive Terpolymer Nano Carrier for Alzheimer’s Treatment," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 48(4), pages 39925-39934, February.
    • Handle: RePEc:abf:journl:v:48:y:2023:i:4:p:39925-39934
    DOI: 10.26717/BJSTR.2023.48.007686
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