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Disruption of Renal Energy Metabolism Dynamics and Histoarchitecture in Diisononyl Phthalate-Exposed Wistar Rats

Author

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  • Samuel Abiodun Kehinde

    (Department of Environmental Health Science, Faculty of Basic Medical Sciences, Ajayi Crowther University, Nigeria
    Department of Chemical Sciences, Faculty of Natural Science, Ajayi Crowther University, Nigeria)

  • Abosede Temitope Olajide

    (Department of Chemical Sciences, Faculty of Natural Science, Ajayi Crowther University, Nigeria)

  • Ayokanmi Ore

    (Department of Chemical Sciences, Faculty of Natural Science, Ajayi Crowther University, Nigeria)

  • Sanmi Tunde Ogunsanya

    (Anatomy Unit, Faculty of Basic Medical Sciences, Ajayi Crowther University, Nigeria)

Abstract

New research indicates that disruption of renal bioenergetics during acute kidney injury (AKI) development is a notable pathophysiologic event, and bioenergetic failure caused by pyruvate depletion is a key mechanism underlying AKI. The aim of this study is to investigate the effect of DiNP on renal energy transduction.

Suggested Citation

  • Samuel Abiodun Kehinde & Abosede Temitope Olajide & Ayokanmi Ore & Sanmi Tunde Ogunsanya, 2023. "Disruption of Renal Energy Metabolism Dynamics and Histoarchitecture in Diisononyl Phthalate-Exposed Wistar Rats," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 48(4), pages 39882-39889, February.
    • Handle: RePEc:abf:journl:v:48:y:2023:i:4:p:39882-39889
    DOI: 10.26717/BJSTR.2023.48.007679
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