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Application of Animal Models in MAFLD

Author

Listed:
  • Li Yuxi

    (School of Basic Medical Sciences North China University of Science and Technology, China)

  • Gao Linghuan

    (North China University of Science and Technology, China)

  • Zhang Haizhu

    (Hebei Key Laboratory for Chronic Diseases, Tangshan Key Laboratory for Preclinical and Basic Research on Chronic Diseases, School of Basic Medical Sciences, North China University of Science and Technology, Tangshan, PR China)

  • Zhang Yuxin

    (North China University of Science and Technology, China)

Abstract

Metabolic dysfunction-Associated Fatty Liver Disease (MAFLD), formerly called non-alcoholic fatty liver disease (NAFLD), and its usually develop to non-alcoholic steatohepatitis (Nonalcoholic steatohepatitis, NASH). MAFLD is not a single disease entity, it belongs to the complication of metabolic syndrome, which is mainly responsible for liver damage, excluding excessive drinking and other clear interventions (such as viruses, drugs, and genetics) [1]. Different from alcoholic fatty liver disease and other toxic fatty liver disease are mainly in the peripheral lobular zone, MAFLD is a widespread diffuse hepatocytic fat change.

Suggested Citation

  • Li Yuxi & Gao Linghuan & Zhang Haizhu & Zhang Yuxin, 2023. "Application of Animal Models in MAFLD," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 48(1), pages 39428-39430, January.
    • Handle: RePEc:abf:journl:v:48:y:2023:i:1:p:39428-39430
    DOI: 10.26717/BJSTR.2023.48.007605
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