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Association between Type 2 Diabetes and KRAS Mutation Status of Colorectal Cancer

Author

Listed:
  • Zeran Yang
  • Meihua Ye
  • Xin Zhang

    (Department of Pathology, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, China)

Abstract

RAS genes (KRAS, NRAS) encoded proteins participate RAS-RAFMAPK signaling pathway. Colorectal cancers (CRC) with RAS mutation are resistant to anti-EGFR monoclonal antibody therapy. The aim of the present study is to determine whether type 2 diabetes (T2DM) linked to RAS mutation of CRC....

Suggested Citation

  • Zeran Yang & Meihua Ye & Xin Zhang, 2022. "Association between Type 2 Diabetes and KRAS Mutation Status of Colorectal Cancer," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 43(4), pages 34791-34798, May.
    • Handle: RePEc:abf:journl:v:43:y:2022:i:4:p:34791-34798
    DOI: 10.26717/BJSTR.2022.43.006933
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