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A New Method for In Vivo Targeted Gene Transfer into Oligodendrocytes using Adenoviral and HIV Vectors

Author

Listed:
  • Koichi Miyake

    (Department of Gene Therapy, Nippon Medical School, Tokyo, Japan)

  • Noriko Miyake
  • Takashi Shimada

    (Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo, Japan)

Abstract

To achieve oligodendrocyte (OL)-specific gene transfer, we applied a two-step method in which target cells were first engineered to express CD4 in a tissue-specific manner using adenoviral....

Suggested Citation

  • Koichi Miyake & Noriko Miyake & Takashi Shimada, 2021. "A New Method for In Vivo Targeted Gene Transfer into Oligodendrocytes using Adenoviral and HIV Vectors," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 39(3), pages 31379-31385, October.
    • Handle: RePEc:abf:journl:v:39:y:2021:i:3:p:31379-31385
    DOI: 10.26717/BJSTR.2021.39.006306
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    More about this item

    Keywords

    Targeted Gene Transfer; Retroviral; Oligodendricytes; Receptor; Adenoviral Vector; Myelin; HIV Vector; Non-Dividing Cells; Ketamine; Serum;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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