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MTHFR677T and 1298C Play Independent but Opposite Effects in Stroke - Additive Co-Effect of two Intragenic Alleles

Author

Listed:
  • Shuo Li
  • Yuming Xu

    (Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, PR China)

  • Edward W Randell
  • Fei-Yu Han

    (Disciplines of Laboratory Medicine, Memorial University of Newfoundland, St. John’s, NL, Canada)

  • Hong Zheng

    (Department of Biology, Faculty of Medicine, Zhengzhou University, Zhengzhou, Henan, P. R. China)

  • Liwen Zou

    (Department of Mathematics and statistics, University of New Brunswick, Saint John, NB, Canada)

  • Ya-Gang Xie

    (Disciplines of Laboratory Medicine, Memorial University of Newfoundland, St. John’s, NL, Canada
    Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada)

Abstract

The MTHFR677C>T variant has been repeatedly shown to associate with cardiovascular disease (CVD) including stroke...

Suggested Citation

  • Shuo Li & Yuming Xu & Edward W Randell & Fei-Yu Han & Hong Zheng & Liwen Zou & Ya-Gang Xie, 2019. "MTHFR677T and 1298C Play Independent but Opposite Effects in Stroke - Additive Co-Effect of two Intragenic Alleles," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 17(1), pages 12563-12569, March.
  • Handle: RePEc:abf:journl:v:17:y:2019:i:1:p:12563-12569
    DOI: 10.26717/BJSTR.2019.17.002954
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    More about this item

    Keywords

    Biomedical Sciences; Biomedical Research; Technical Research; MTHFR Gene Variants; Ischemic Stroke; Association; Additive Co-Effect of Intragenic Allele-Allele Interaction;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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