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Direct Access to New Gem-Difluorinated Pyrido[1,2-a] Pyrimidine-2-one Systems

Author

Listed:
  • Ranin Kawtharani
  • Mohamed Abarbri

    (Laboratoire de Physico-Chimie des Matériaux et des Electrolytes pour l’Energie (PCM2E), France)

  • Ranin Kawtharani
  • Mirvat Elmasri
  • Ali Hachem

    (Laboratoire de Chimie Médicinale et de Produit naturels, (LCMPN) Lebanon)

  • Khalil Cherry

    (Laboratoire Matériaux, Catalyse, Environnement et Méthodes Analytiques (MCEMA), Lebanon)

Abstract

Efficient method for the synthesis of gem-difluorinated pyrido[1,2-a]pyrimidine- 2-ones using addition/heterocyclization followed by Heck and Suzuki cross coupling reactions is reported...

Suggested Citation

  • Ranin Kawtharani & Mohamed Abarbri & Ranin Kawtharani & Mirvat Elmasri & Ali Hachem & Khalil Cherry, 2019. "Direct Access to New Gem-Difluorinated Pyrido[1,2-a] Pyrimidine-2-one Systems," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 16(3), pages 12063-12080, March.
    • Handle: RePEc:abf:journl:v:16:y:2019:i:3:p:12063-12080
    DOI: 10.26717/BJSTR.2019.16.002859
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    Keywords

    Biomedical Sciences; Biomedical Research; Technical Research; Gem-Difluorinated Pyrido[1; 2-a]Pyrimidine-2-Ones; 2-Aminopyridines; Gem-Difluorinated Alkynes; Heck Reaction; Suzuki Reaction;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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