The path- and place-dependent nature of scientific knowledge production in biotech 1986-2008
AbstractThis study explores the worldwide spatial evolution of scientific knowledge production in biotechnology in the period 1986-2008. We employ new methodology that identifies new key topics in biotech on the basis of frequent use of title worlds in major biotech journals as an indication of new cognitive developments within this scientific field. Our analyses show that biotech is subject to a path- and place-dependent process of knowledge production. We observed a high degree of re-occurrences of similar key topics in biotech in consecutive years. Furthermore, slow growth cities in biotech are characterized by topics that are less technologically related to other topics, while high growth cities in biotech contribute to topics that are more related to the entire set of existing topics. Slow growth and stable growth cities in biotech introduced more new topics, while fast growth cities in biotech introduced more promising topics. Slow growth cities also showed low levels of research collaboration, as compared to stable and high growth cities.
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Bibliographic InfoPaper provided by Utrecht University, Section of Economic Geography in its series Papers in Evolutionary Economic Geography (PEEG) with number 1210.
Length: 50 pages
Date of creation: Jun 2012
Date of revision: Jun 2012
title words; branching; geography of biotechnology; scientific knowledge production; path dependence; place dependence;
Find related papers by JEL classification:
- O33 - Economic Development, Technological Change, and Growth - - Technological Change; Research and Development; Intellectual Property Rights - - - Technological Change: Choices and Consequences; Diffusion Processes
- R11 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General Regional Economics - - - Regional Economic Activity: Growth, Development, Environmental Issues, and Changes
- L65 - Industrial Organization - - Industry Studies: Manufacturing - - - Chemicals; Rubber; Drugs; Biotechnology
- D83 - Microeconomics - - Information, Knowledge, and Uncertainty - - - Search, Learning, and Information
This paper has been announced in the following NEP Reports:
- NEP-ALL-2012-06-13 (All new papers)
- NEP-CSE-2012-06-13 (Economics of Strategic Management)
- NEP-KNM-2012-06-13 (Knowledge Management & Knowledge Economy)
- NEP-URE-2012-06-13 (Urban & Real Estate Economics)
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- Cooke, Philip, 2001. "Regional Innovation Systems, Clusters, and the Knowledge Economy," Industrial and Corporate Change, Oxford University Press, vol. 10(4), pages 945-74, December.
- Jackie Krafft & Francesco Quatraro & Pier-Paolo Saviotti, 2011.
"The Knowledge Base Evolution in Biotechnology: A Social Network Analysis,"
- Jackie Krafft & Francesco Quatraro & Pier Paolo Saviotti, 2011. "The knowledge-base evolution in biotechnology: a social network analysis," Economics of Innovation and New Technology, Taylor & Francis Journals, vol. 20(5), pages 445-475.
- Jarno Hoekman & Koen Frenken & Frank Oort, 2009.
"The geography of collaborative knowledge production in Europe,"
The Annals of Regional Science,
Springer, vol. 43(3), pages 721-738, September.
- Jarno Hoekman & Koen Frenken & Frank van Oort, 2008. "The geography of collaborative knowledge production in Europe," KITeS Working Papers 214, KITeS, Centre for Knowledge, Internationalization and Technology Studies, Universita' Bocconi, Milano, Italy, revised Feb 2008.
- Dominique Foray, 2006. "The Economics of Knowledge," MIT Press Books, The MIT Press, edition 1, volume 1, number 0262562235, June.
- Steven Klepper, 2007. "Disagreements, Spinoffs, and the Evolution of Detroit as the Capital of the U.S. Automobile Industry," Management Science, INFORMS, vol. 53(4), pages 616-631, April.
- Bjørn Asheim, . "Industrial Districts as 'learning regions'. A condition for prosperity," STEP Report series 199503, The STEP Group, Studies in technology, innovation and economic policy.
- Michaela Trippl, 2009. "Islands of Innovation and Internationally Networked Labor Markets: Magnetic Centers for Star Scientists?," SRE-Disc sre-disc-2009_06, Institute for the Environment and Regional Development, Department of Socioeconomics, Vienna University of Economics and Business.
- Roberta Capello, 1999. "Spatial Transfer of Knowledge in High Technology Milieux: Learning Versus Collective Learning Processes," Regional Studies, Taylor and Francis Journals, vol. 33(4), pages 353-365.
- Meric S. Gertler, 2003. "Tacit knowledge and the economic geography of context, or The undefinable tacitness of being (there)," Journal of Economic Geography, Oxford University Press, vol. 3(1), pages 75-99, January.
- Ron Boschma & Simona Iammarino, 2009. "Related Variety, Trade Linkages, and Regional Growth in Italy," Economic Geography, Clark University, vol. 85(3), pages 289-311, 07.
- M. S. Gertler & Y. M. Levitte, 2005. "Local Nodes in Global Networks: The Geography of Knowledge Flows in Biotechnology Innovation," Industry & Innovation, Taylor and Francis Journals, vol. 12(4), pages 487-507.
- repec:oxf:wpaper:084 is not listed on IDEAS
- Philip McCann, 2007. "Globalization and economic geography: the world is curved, not flat," Cambridge Journal of Regions, Economy and Society, Cambridge Political Economy Society, vol. 1(3), pages 351-370.
- Stefano Breschi & Francesco Lissoni, 2009. "Mobility of skilled workers and co-invention networks: an anatomy of localized knowledge flows," Journal of Economic Geography, Oxford University Press, vol. 9(4), pages 439-468, July.
- Frank Neffke & Martin Henning & Ron Boschma, 2011.
"How Do Regions Diversify over Time? Industry Relatedness and the Development of New Growth Paths in Regions,"
Clark University, vol. 87(3), pages 237-265, 07.
- Frank Neffke & Martin Henning & Martin Ron Boschma, 2009. "How do regions diversify over time? Industry relatedness and the development of new growth paths in regions," Papers in Evolutionary Economic Geography (PEEG) 0916, Utrecht University, Section of Economic Geography, revised Oct 2009.
- C. A. Hidalgo & B. Klinger & A. -L. Barabasi & R. Hausmann, 2007. "The Product Space Conditions the Development of Nations," Papers 0708.2090, arXiv.org.
- Ron Boschma & Asier Minondo & Mikel Navarro, 2012. "The emergence of new industries at the regional level in Spain. A proximity approach based on product-relatedness," Papers in Evolutionary Economic Geography (PEEG) 1201, Utrecht University, Section of Economic Geography, revised Jan 2012.
- Breschi, Stefano & Lissoni, Francesco & Malerba, Franco, 2003. "Knowledge-relatedness in firm technological diversification," Research Policy, Elsevier, vol. 32(1), pages 69-87, January.
- Phil Cooke, 2006. "Global Bioregions: Knowledge Domains, Capabilities and Innovation System Networks," Industry & Innovation, Taylor and Francis Journals, vol. 13(4), pages 437-458.
- Ron Boschma & Gaston Heimeriks & Pierre-Alexandre Balland, 2013. "Scientific Knowledge Dynamics and Relatedness in Bio-Tech Cities," Papers in Evolutionary Economic Geography (PEEG) 1304, Utrecht University, Section of Economic Geography, revised Apr 2013.
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