Advanced Search
MyIDEAS: Login

The knowledge-base evolution in biotechnology: a social network analysis

Contents:

Author Info

  • Jackie Krafft
  • Francesco Quatraro
  • Pier Paolo Saviotti

Abstract

This paper applies the methodological tools typical of social network analysis (SNA) within an evolutionary framework, to investigate the knowledge-base (KB) dynamics of the biotechnology sector. Knowledge is here considered a collective good represented as a co-relational and a retrieval-interpretative structure. The internal structure of knowledge is described as a network, the nodes of which are small units within traces of knowledge, such as patent documents, connected by links determined by their joint utilization. We used measures referring to the network (like density) and to its nodes (like degree, closeness and betweenness centrality) to provide a synthetic description of the structure of the KB and of its evolution over time. Eventually, we compared such measures with more established properties of the KB calculated on the basis of co-occurrences of technological classes within patent documents. Empirical results show the existence of interesting and meaningful relationships across the different measures, providing support for the use of SNA to study the evolution of the KBs of industrial sectors and their lifecycles.

Download Info

If you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
File URL: http://www.tandfonline.com/doi/abs/10.1080/10438599.2011.562355
Download Restriction: Access to full text is restricted to subscribers.

As the access to this document is restricted, you may want to look for a different version under "Related research" (further below) or search for a different version of it.

Bibliographic Info

Article provided by Taylor & Francis Journals in its journal Economics of Innovation and New Technology.

Volume (Year): 20 (2011)
Issue (Month): 5 ()
Pages: 445-475

as in new window
Handle: RePEc:taf:ecinnt:v:20:y:2011:i:5:p:445-475

Contact details of provider:
Web page: http://www.tandfonline.com/GEIN20

Order Information:
Web: http://www.tandfonline.com/pricing/journal/GEIN20

Related research

Keywords: knowledge base; social network analysis; variety; coherence; industry lifecycles; exploration/exploitation;

Other versions of this item:

References

References listed on IDEAS
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
as in new window
  1. repec:fth:harver:1473 is not listed on IDEAS
  2. Gert Sabidussi, 1966. "The centrality index of a graph," Psychometrika, Springer, vol. 31(4), pages 581-603, December.
  3. Breschi, Stefano & Lissoni, Francesco & Malerba, Franco, 2003. "Knowledge-relatedness in firm technological diversification," Research Policy, Elsevier, vol. 32(1), pages 69-87, January.
  4. Olsson, Ola, 2000. " Knowledge as a Set in Idea Space: An Epistemological View on Growth," Journal of Economic Growth, Springer, vol. 5(3), pages 253-75, September.
  5. Frenken, K. & Nuvolari, A., 2002. "Entropy Statistics as a Framework to Analyse Technological Evolution," Eindhoven Center for Innovation Studies (ECIS) working paper series 02.15, Eindhoven Center for Innovation Studies (ECIS).
  6. Teece, David J. & Rumelt, Richard & Dosi, Giovanni & Winter, Sidney, 1994. "Understanding corporate coherence : Theory and evidence," Journal of Economic Behavior & Organization, Elsevier, vol. 23(1), pages 1-30, January.
  7. Acs, Zoltan J. & Anselin, Luc & Varga, Attila, 2002. "Patents and innovation counts as measures of regional production of new knowledge," Research Policy, Elsevier, vol. 31(7), pages 1069-1085, September.
  8. Pier Saviotti & Koen Frenken, 2008. "Export variety and the economic performance of countries," Journal of Evolutionary Economics, Springer, vol. 18(2), pages 201-218, April.
  9. Elisa Giuliani, 2007. "The selective nature of knowledge networks in clusters: evidence from the wine industry," Journal of Economic Geography, Oxford University Press, vol. 7(2), pages 139-168, March.
  10. Koen Frenken & Frank Van Oort & Thijs Verburg, 2007. "Related Variety, Unrelated Variety and Regional Economic Growth," Regional Studies, Taylor & Francis Journals, vol. 41(5), pages 685-697.
  11. Nesta, Lionel, 2008. "Knowledge and productivity in the world's largest manufacturing corporations," Journal of Economic Behavior & Organization, Elsevier, vol. 67(3-4), pages 886-902, September.
  12. Krafft, Jackie, 2004. "Entry, exit and knowledge: evidence from a cluster in the info-communications industry," Research Policy, Elsevier, vol. 33(10), pages 1687-1706, December.
  13. Andrea Morrison, 2008. "Gatekeepers of Knowledge within Industrial Districts: Who They Are, How They Interact," Regional Studies, Taylor & Francis Journals, vol. 42(6), pages 817-835.
  14. Saviotti, P. P., 1988. "Information, variety and entropy in technoeconomic development," Research Policy, Elsevier, vol. 17(2), pages 89-103, April.
  15. Fleming, Lee & Sorenson, Olav, 2001. "Technology as a complex adaptive system: evidence from patent data," Research Policy, Elsevier, vol. 30(7), pages 1019-1039, August.
  16. Zvi Griliches, 1991. "Patent Statistics as Economic Indicators: A Survey," NBER Working Papers 3301, National Bureau of Economic Research, Inc.
  17. Thomas Grebel & Jackie Krafft & Pier-Paolo Saviotti, 2006. "On the Life Cycle of Knowledge Intensive Sectors," Revue de l'OFCE, Presses de Sciences-Po, vol. 97(5), pages 63-85.
  18. Saviotti, Pier Paolo, 2007. "On the dynamics of generation and utilisation of knowledge: The local character of knowledge," Structural Change and Economic Dynamics, Elsevier, vol. 18(4), pages 387-408, December.
  19. Jackie Krafft & Francesco Quatraro, 2011. "The dynamics of technological knowledge," Post-Print halshs-00727633, HAL.
  20. Krafft, Jackie & Quatraro, Francesco & Saviotti, Paolo, 2009. "Evolution of the Knowledge Base in Knowledge Intensive Sectors," Department of Economics and Statistics Cognetti de Martiis LEI & BRICK - Laboratory of Economics of Innovation "Franco Momigliano", Bureau of Research in Innovation, Complexity and Knowledge, Collegio 200906, University of Turin.
Full references (including those not matched with items on IDEAS)

Citations

Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
as in new window

Cited by:
  1. Consoli,Davide & Elche,Dioni, 2014. "An analysis of the knowledge base of Scientific Research & Development Business Services," INGENIO (CSIC-UPV) Working Paper Series 201401, INGENIO (CSIC-UPV).
  2. Francesco Quatraro, 2012. "The Co-Evolution of Knowledge and Economic Structure: Evidence from European Regions," GREDEG Working Papers 2012-16, Groupe de REcherche en Droit, Économie, Gestion (GREDEG CNRS), University of Nice Sophia Antipolis.
  3. Colombelli Alessandra & Krafft.Jackie & Quatraro Francesco, 2012. "Properties of knowledge base and firm survival: Evidence from a sample of French manufacturing firms," Department of Economics and Statistics Cognetti de Martiis LEI & BRICK - Laboratory of Economics of Innovation "Franco Momigliano", Bureau of Research in Innovation, Complexity and Knowledge, Collegio 201209, University of Turin.
  4. Antonelli, Cristiano, 2013. "Globalization Localized Technological Change and the Knowledge Economy," Department of Economics and Statistics Cognetti de Martiis LEI & BRICK - Laboratory of Economics of Innovation "Franco Momigliano", Bureau of Research in Innovation, Complexity and Knowledge, Collegio 201312, University of Turin.
  5. Boschma, Ron & Heimeriks, Gaston & Balland, Pierre-Alexandre, 2014. "Scientific knowledge dynamics and relatedness in biotech cities," Research Policy, Elsevier, vol. 43(1), pages 107-114.
  6. Ron Boschma & Pierre-Alexandre Balland & Dieter Franz Kogler, 2013. "Relatedness and Technological Change in Cities: The rise and fall of technological knowledge in U.S. metropolitan areas from 1981 to 2010," Papers in Evolutionary Economic Geography (PEEG) 1316, Utrecht University, Section of Economic Geography, revised Sep 2013.
  7. Alessandra Colombelli & Jackie Krafft & Francesco Quatraro, 2012. "High Growth Firms and Technological Knowledge: Do gazelles follow exploration or exploitation strategies?," Working Papers hal-00666707, HAL.
  8. repec:hal:wpaper:hal-00686007 is not listed on IDEAS
  9. Michael Dietrich & Jackie Krafft, 2012. "Economics and Theory of the Firm, Chap. 1 of the Handbook on Economics and Theory of the Firm, M. Dietrich and Jackie Krafft (eds), Edward Elgar: Cheltenham, 2012," Post-Print halshs-00742302, HAL.
  10. Colombelli Alessandra & Quatraro Francesco, 2012. "Persistence of innovation and knowledge structure: Evidence from a sample of Italian firms," Department of Economics and Statistics Cognetti de Martiis LEI & BRICK - Laboratory of Economics of Innovation "Franco Momigliano", Bureau of Research in Innovation, Complexity and Knowledge, Collegio 201205, University of Turin.
  11. Francesco Quatraro, 2011. "Knowledge Structure and Regional Economic Growth: The French case," Post-Print halshs-00727630, HAL.
  12. Quatraro, Francesco, 2010. "Knowledge coherence, variety and economic growth: Manufacturing evidence from Italian regions," Research Policy, Elsevier, vol. 39(10), pages 1289-1302, December.
  13. Gaston Heimeriks & Ron Boschma, 2012. "The path- and place-dependent nature of scientific knowledge production in biotech 1986-2008," Papers in Evolutionary Economic Geography (PEEG) 1210, Utrecht University, Section of Economic Geography, revised Jun 2012.
  14. Alessandra Colombelli & Francesco Quatraro, 2013. "The persistence of firms' knowledge base: A quantile approach to Italian data," Working Papers hal-00867132, HAL.

Lists

This item is not listed on Wikipedia, on a reading list or among the top items on IDEAS.

Statistics

Access and download statistics

Corrections

When requesting a correction, please mention this item's handle: RePEc:taf:ecinnt:v:20:y:2011:i:5:p:445-475. See general information about how to correct material in RePEc.

For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Michael McNulty).

If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

If references are entirely missing, you can add them using this form.

If the full references list an item that is present in RePEc, but the system did not link to it, you can help with this form.

If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your profile, as there may be some citations waiting for confirmation.

Please note that corrections may take a couple of weeks to filter through the various RePEc services.