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COHERENCE OF THE KNOWLEDGE BASE AND THE FIRM'S INNOVATIVE PERFORMANCE: EVIDENCE FROM THE U.S. PHARMACEUTICAL INDUSTRY -super-*

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Author Info

  • Lionel Nesta
  • Pier Paolo Saviotti

Abstract

We examine the relationship between the coherence of the knowledge base and the innovative performance of U.S. pharmaceutical firms during the 1990's. We develop measures of the coherence and scope of the firms' knowledge base. Count data regression models show a strong link between these two properties and the firms' innovative performance. Firms experience decreasing returns to scale in research but larger firms enjoy a significant size advantage in innovation. Knowledge flows are necessary in knowledge production but not sufficient to secure its quality. Over time, the contribution of the scope and coherence of the knowledge base is increasing. Copyright Blackwell Publishing Ltd. 2005.

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Bibliographic Info

Article provided by Wiley Blackwell in its journal The Journal of Industrial Economics.

Volume (Year): 53 (2005)
Issue (Month): 1 (03)
Pages: 123-142

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Handle: RePEc:bla:jindec:v:53:y:2005:i:1:p:123-142

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Web page: http://www.blackwellpublishing.com/journal.asp?ref=0022-1821

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Cited by:
  1. Leten, Bart & Kelchtermans, Stijn & Belderbos, Ren, 2010. "Internal Basic Research, External Basic Research and the Technological Performance of Pharmaceutical Firms," Working Papers 2010/12, Hogeschool-Universiteit Brussel, Faculteit Economie en Management.
  2. Thomas Grebel & Jackie Krafft & Pier-Paolo Saviotti, 2006. "On knowledge intensive industry life cycles," Post-Print hal-00203585, HAL.
  3. Cristiano Antonelli & Jackie Krafft & Francesco Quatraro, 2010. "Recombinant Knowledge and Growth: The Case of ICTs," Post-Print hal-00448649, HAL.
  4. Lionel Nesta & Vincent Mangematin, 2003. "Industry Life Cycle, Knowledge Generation and Technological Networks," Post-Print hal-00424163, HAL.
  5. Suzuki, Shinya, 2012. "Internationalization of R&D activities by multinational firms.," Open Access publications from Katholieke Universiteit Leuven urn:hdl:123456789/340794, Katholieke Universiteit Leuven.
  6. Lokshin, Boris & Belderbos, René & Carree, Martin, 2008. "The productivity effects of internal and external R&D: evidence from a dynamic panel data model," Open Access publications from Maastricht University urn:nbn:nl:ui:27-20504, Maastricht University.
  7. Reinhard Haupt & Matthias Korgel, 2005. "A Comparison between US and International Patent Classification as Input Data of a Technology Competition-Oriented Cluster Analysis," Jenaer Schriften zur Wirtschaftswissenschaft 20/2005, Friedrich-Schiller-Universität Jena, Wirtschaftswissenschaftliche Fakultät.
  8. Boris Lokshin & Rene Belderbos & Martin Carree, 2006. "Internal and external R&D： complements or substitutes? Evidence from a dynamic panel data model," Hi-Stat Discussion Paper Series d06-163, Institute of Economic Research, Hitotsubashi University.
  9. Evens Salies & Lionel Nesta, 2010. "Libéralisation et dépôts de brevets verts des utilités électriques en Europe," Documents de Travail de l'OFCE 2010-21, Observatoire Francais des Conjonctures Economiques (OFCE).
  10. Elisa Giuliani, 2005. "The Structure of Cluster Knowledge Networks Uneven, not Pervasive and Collective," DRUID Working Papers 05-11, DRUID, Copenhagen Business School, Department of Industrial Economics and Strategy/Aalborg University, Department of Business Studies.
  11. Lionel Nesta & Pier-Paolo Saviotti, 2003. "Intangible Assests and Market Value: Evidence from Biotechnology Firms," SPRU Working Paper Series 87, SPRU - Science and Technology Policy Research, University of Sussex.
  12. Quatraro Francesco, 2008. "Regional Knowledge base and productivity growth: the evidence of italian manufacturing," Dipartimento di Economia "S. Cognetti de Martiis" LEI & BRICK - Laboratorio di economia dell'innovazione "Franco Momigliano", Bureau of Research in Innovation, Complexity and Knowledge, Collegio Carlo 200810, University of Turin.

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