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Specification of random effects in multilevel models: a review

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  • Leonardo Grilli
  • Carla Rampichini

Abstract

The analysis of highly structured data requires models with unobserved components (random effects) able to adequately account for the patterns of variances and correlations. The specification of the unobserved components is a key and challenging task. In this paper, we first review the literature about the consequences of misspecifying the distribution of the random effects and the related diagnostic tools; we then outline the main alternatives and generalizations, also considering some issues arising in Bayesian inference. The relevance of suitably structuring the unobserved components is illustrated by means of an application exploiting a model with heteroscedastic random effects. Copyright Springer Science+Business Media Dordrecht 2015

Suggested Citation

  • Leonardo Grilli & Carla Rampichini, 2015. "Specification of random effects in multilevel models: a review," Quality & Quantity: International Journal of Methodology, Springer, vol. 49(3), pages 967-976, May.
  • Handle: RePEc:spr:qualqt:v:49:y:2015:i:3:p:967-976
    DOI: 10.1007/s11135-014-0060-5
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    1. Murray Aitkin, 1999. "A General Maximum Likelihood Analysis of Variance Components in Generalized Linear Models," Biometrics, The International Biometric Society, vol. 55(1), pages 117-128, March.
    2. Huang, Xianzheng, 2011. "Detecting random-effects model misspecification via coarsened data," Computational Statistics & Data Analysis, Elsevier, vol. 55(1), pages 703-714, January.
    3. Saskia Litière & Ariel Alonso & Geert Molenberghs, 2011. "Rejoinder to “A Note on Type II Error Under Random Effects Misspecification in Generalized Linear Mixed Models”," Biometrics, The International Biometric Society, vol. 67(2), pages 656-660, June.
    4. Verbeke, Geert & Lesaffre, Emmanuel, 1997. "The effect of misspecifying the random-effects distribution in linear mixed models for longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 23(4), pages 541-556, February.
    5. Jee-Seon Kim & Edward Frees, 2007. "Multilevel Modeling with Correlated Effects," Psychometrika, Springer;The Psychometric Society, vol. 72(4), pages 505-533, December.
    6. Julian Besag & Jeremy York & Annie Mollié, 1991. "Bayesian image restoration, with two applications in spatial statistics," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 43(1), pages 1-20, March.
    7. Antic, J. & Laffont, C.M. & Chafaï, D. & Concordet, D., 2009. "Comparison of nonparametric methods in nonlinear mixed effects models," Computational Statistics & Data Analysis, Elsevier, vol. 53(3), pages 642-656, January.
    8. Peter Ebbes & Ulf Böckenholt & Michel Wedel, 2004. "Regressor and random‐effects dependencies in multilevel models," Statistica Neerlandica, Netherlands Society for Statistics and Operations Research, vol. 58(2), pages 161-178, May.
    9. Cora J. M. Maas & Joop J. Hox, 2004. "Robustness issues in multilevel regression analysis," Statistica Neerlandica, Netherlands Society for Statistics and Operations Research, vol. 58(2), pages 127-137, May.
    10. Bruno ARPINO & Roberta VARRIALE, 2010. "Assessing The Quality Of Institutions’ Rankings Obtained Through Multilevel Linear Regression Models," Journal of Applied Economic Sciences, Spiru Haret University, Faculty of Financial Management and Accounting Craiova, vol. 5(1(11)_Spr), pages 7-22.
    11. Laura Azzimonti & Francesca Ieva & Anna Maria Paganoni, 2013. "Nonlinear nonparametric mixed-effects models for unsupervised classification," Computational Statistics, Springer, vol. 28(4), pages 1549-1570, August.
    12. Alessandra Guglielmi & Francesca Ieva & Anna M. Paganoni & Fabrizio Ruggeri & Jacopo Soriano, 2014. "Semiparametric Bayesian models for clustering and classification in the presence of unbalanced in-hospital survival," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 63(1), pages 25-46, January.
    13. Lesperance, Mary & Saab, Rabih & Neuhaus, John, 2014. "Nonparametric estimation of the mixing distribution in logistic regression mixed models with random intercepts and slopes," Computational Statistics & Data Analysis, Elsevier, vol. 71(C), pages 211-219.
    14. Francesco Bartolucci & Fulvia Pennoni & Giorgio Vittadini, 2011. "Assessment of School Performance Through a Multilevel Latent Markov Rasch Model," Journal of Educational and Behavioral Statistics, , vol. 36(4), pages 491-522, August.
    15. George Leckie & Harvey Goldstein, 2009. "The limitations of using school league tables to inform school choice," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 172(4), pages 835-851, October.
    16. William Browne & Harvey Goldstein, 2010. "MCMC Sampling for a Multilevel Model With Nonindependent Residuals Within and Between Cluster Units," Journal of Educational and Behavioral Statistics, , vol. 35(4), pages 453-473, August.
    17. Agresti, Alan & Caffo, Brian & Ohman-Strickland, Pamela, 2004. "Examples in which misspecification of a random effects distribution reduces efficiency, and possible remedies," Computational Statistics & Data Analysis, Elsevier, vol. 47(3), pages 639-653, October.
    18. Donald Hedeker & Robin J. Mermelstein & Hakan Demirtas, 2008. "An Application of a Mixed-Effects Location Scale Model for Analysis of Ecological Momentary Assessment (EMA) Data," Biometrics, The International Biometric Society, vol. 64(2), pages 627-634, June.
    19. George Leckie & Harvey Goldstein, 2011. "Understanding Uncertainty in School League Tables," Fiscal Studies, Institute for Fiscal Studies, vol. 32(2), pages 207-224, June.
    20. Xianzheng Huang, 2009. "Diagnosis of Random-Effect Model Misspecification in Generalized Linear Mixed Models for Binary Response," Biometrics, The International Biometric Society, vol. 65(2), pages 361-368, June.
    21. Fabienne Comte & Adeline Samson, 2012. "Nonparametric estimation of random-effects densities in linear mixed-effects model," Journal of Nonparametric Statistics, Taylor & Francis Journals, vol. 24(4), pages 951-975, December.
    22. Daowen Zhang & Marie Davidian, 2001. "Linear Mixed Models with Flexible Distributions of Random Effects for Longitudinal Data," Biometrics, The International Biometric Society, vol. 57(3), pages 795-802, September.
    23. Komárek, Arnost & Lesaffre, Emmanuel, 2008. "Generalized linear mixed model with a penalized Gaussian mixture as a random effects distribution," Computational Statistics & Data Analysis, Elsevier, vol. 52(7), pages 3441-3458, March.
    24. Eberly, Lynn E. & Thackeray, Lisa M., 2005. "On Lange and Ryan's plotting technique for diagnosing non-normality of random effects," Statistics & Probability Letters, Elsevier, vol. 75(2), pages 77-85, November.
    25. Hall, Peter & Yao, Qiwei, 2003. "Inference in components of variance models with low replication," LSE Research Online Documents on Economics 17701, London School of Economics and Political Science, LSE Library.
    26. Jacqmin-Gadda, Helene & Sibillot, Solenne & Proust, Cecile & Molina, Jean-Michel & Thiebaut, Rodolphe, 2007. "Robustness of the linear mixed model to misspecified error distribution," Computational Statistics & Data Analysis, Elsevier, vol. 51(10), pages 5142-5154, June.
    27. Alonso, Ariel & Litière, Saskia & Laenen, Annouschka, 2010. "A Note on the Indeterminacy of the Random-Effects Distribution in Hierarchical Models," The American Statistician, American Statistical Association, vol. 64(4), pages 318-324.
    28. Wendimagegn Ghidey & Emmanuel Lesaffre & Paul Eilers, 2004. "Smooth Random Effects Distribution in a Linear Mixed Model," Biometrics, The International Biometric Society, vol. 60(4), pages 945-953, December.
    29. Nicole White & Helen Johnson & Peter Silburn & Kerrie Mengersen, 2012. "Dirichlet process mixture models for unsupervised clustering of symptoms in Parkinson's disease," Journal of Applied Statistics, Taylor & Francis Journals, vol. 39(11), pages 2363-2377, July.
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    Cited by:

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    2. Sandra De Iaco & Sabrina Maggio, 2022. "Using multilevel models to evaluate the attitude of separate waste collection in young people," METRON, Springer;Sapienza Università di Roma, vol. 80(1), pages 77-95, April.
    3. Andrew Bell & Malcolm Fairbrother & Kelvyn Jones, 2019. "Fixed and random effects models: making an informed choice," Quality & Quantity: International Journal of Methodology, Springer, vol. 53(2), pages 1051-1074, March.
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    5. Shuwen Hu & You-Gan Wang & Christopher Drovandi & Taoyun Cao, 2023. "Predictions of machine learning with mixed-effects in analyzing longitudinal data under model misspecification," Statistical Methods & Applications, Springer;Società Italiana di Statistica, vol. 32(2), pages 681-711, June.

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