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Feasibility and Reliability of the Annual Profile Method for Deriving QALYs for Short-Term Health Conditions

Author

Listed:
  • Mathieu F. Janssen

    (Department of Social Medicine-Public Health Epidemiology, Academic Medical Center, Amsterdam, the Netherlands, m.f.janssen@amc.uva.nl)

  • Erwin Birnie

    (Department of Social Medicine-Public Health Epidemiology, Academic Medical Center, Amsterdam, the Netherlands, Institute of Health Policy and Management, Erasmus Medical Center, Rotterdam, the Netherlands)

  • Gouke Bonsel

    (Department of Social Medicine-Public Health Epidemiology, Academic Medical Center, Amsterdam, the Netherlands, Institute of Health Policy and Management, Erasmus Medical Center, Rotterdam, the Netherlands)

Abstract

Introduction . When health varies over time, the standard quality-adjusted life year model operates under the assumptions of time utility independence within each health state and additive independence between health states. These assumptions can be relaxed by an integral assessment of disease severity over time. The authors present the annual profile method (APM), which values health profiles on a 1-year base, and test the APM for feasibility, consistency, and test-retest reliability. Methods . A population panel, general practitioners, medical advisers, and a panel of the Dutch Consumers Association valued vignettes for 46 disease stages using the visual analog scale (VAS) and time tradeoff (TTO) methods. Vignettes contained disease-specific information, a generic description (EQ-6D5L), a description of the disease course over time, and a visual representation of the disease. Feasibility was tested by missing and inconsistent responses. Consistency between and within panels was tested with a generalizability study, analysis of variance, and standard correlation coefficients. Test-retest reliability was tested with a generalizability study and intra-class correlation coefficients. Results . Missing and inconsistent responses were

Suggested Citation

  • Mathieu F. Janssen & Erwin Birnie & Gouke Bonsel, 2008. "Feasibility and Reliability of the Annual Profile Method for Deriving QALYs for Short-Term Health Conditions," Medical Decision Making, , vol. 28(4), pages 500-510, July.
    • Handle: RePEc:sae:medema:v:28:y:2008:i:4:p:500-510
    DOI: 10.1177/0272989X07312711
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    References listed on IDEAS

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    1. Bleichrodt, Han, 1995. "QALYs and HYEs: Under what conditions are they equivalent?," Journal of Health Economics, Elsevier, vol. 14(1), pages 17-37, May.
    2. Keeney,Ralph L. & Raiffa,Howard, 1993. "Decisions with Multiple Objectives," Cambridge Books, Cambridge University Press, number 9780521438834.
    3. Drummond, Michael F. & Sculpher, Mark J. & Torrance, George W. & O'Brien, Bernie J. & Stoddart, Greg L., 2005. "Methods for the Economic Evaluation of Health Care Programmes," OUP Catalogue, Oxford University Press, edition 3, number 9780198529453.
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    Cited by:

    1. Bas Janssen & Mark Oppe & Matthijs Versteegh & Elly Stolk, 2013. "Introducing the composite time trade-off: a test of feasibility and face validity," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 14(1), pages 5-13, July.
    2. Koonal K. Shah & Bryan Bennett & Andrew Lenny & Louise Longworth & John E. Brazier & Mark Oppe & A. Simon Pickard & James W. Shaw, 2021. "Adapting preference-based utility measures to capture the impact of cancer treatment-related symptoms," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 22(8), pages 1301-1309, November.

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