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1000 Days: The “WeCare Generation” Program—The Ultimate Model for Improving Human Mental Health and Economics: The Study Protocol

Author

Listed:
  • Orlando Uccellini

    (Department of Mental Health, ASST Brianza, 20871 Vimercate, Italy)

  • Andrea Benlodi

    (Clinical Psychology Unit Carlo Poma Hospital, ASST Mantova, 46100 Mantua, Italy)

  • Emanuele Caroppo

    (Department of Mental Health, Local Health Authority Roma 2, 00159 Rome, Italy)

  • Loredana Cena

    (Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy)

  • Gianluca Esposito

    (Department of Psychology and Cognitive Science, University of Trento, 38122 Trent, Italy)

  • Isabel Fernandez

    (EMDR Italia Association, 20814 Varedo, Italy)

  • Maria Ghazanfar

    (Maternal and Child Department, ASST Brianza, 20871 Vimercate, Italy)

  • Antonio Imbasciati

    (Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy)

  • Francesco Longo

    (Cergas Center for Research on Health and Social Care Management, SDA Bocconi University, 20136 Milan, Italy)

  • Marianna Mazza

    (Department of Geriatrics, Neuroscience and Orthopedics, Institute of Psychiatry and Psychology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Universita’ Cattolica del Sacro Cuore, 00168 Rome, Italy)

  • Giuseppe Marano

    (Department of Geriatrics, Neuroscience and Orthopedics, Institute of Psychiatry and Psychology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Universita’ Cattolica del Sacro Cuore, 00168 Rome, Italy)

  • Renata Nacinovich

    (Child and Adolescent Neuropsichiatry, ASST Monza, NeuroMI—Milan Center for Neuroscience, University of Milano Bicocca, 20126 Milan, Italy)

  • Antonio Pignatto

    (Department of Psychology, IUSTO—Salesian University Institute Torino Rebaudengo, 10155 Turin, Italy)

  • Arthur Rolnick

    (Department of Economics, Humphrey School of Public Affairs, University of Minnesota, Minneapolis, MN 55455, USA)

  • Marco Trivelli

    (General and Economic Direction, ASST Brianza, 20871 Vimercate, Italy)

  • Elena Spada

    (Magistica, 23875 Lecco, Italy)

  • Cinzia Vanzini

    (Training Sector Management, ASST Brianza, 20871 Vimercate, Italy)

Abstract

Introduction: The COVID-19 pandemic stressed the necessity of a new resilience of the human population and health system. The “WeCare Generation” program is a new proposal of territorial intervention, with a new paradigm, on the diseases of the human body and mind. Background: In recent decades, the independent strands of investigation on brain plasticity and early trauma consequences have demonstrated that traumatic experiences in the period from pregnancy to the age of 3 years have an enormous impact on an individual’s future development, and both physical and mental health. Research shows that adverse child experiences (ACEs) are associated with a strong risk of conditions such as: harmful alcohol use, smoking, illicit drug use, high body-mass index, depression, anxiety, interpersonal violence, cancer, type 2 diabetes, cardiovascular diseases, stroke respiratory diseases and, as a consequence, to a high financial cost in Italy and also across Europe (1–9% GDP) and the USA (total annual costs estimated to be USD 581 billion in Europe and USD 748 billion in North America). All this suggests that an early intervention on that traumatized-slice of population leads to multiplied savings. Methods: A multi-center, randomized, controlled trial was designed. The parents of the future neonatal population (from pregnancy to delivery) with trauma will be enrolled, and randomized to treatment, or control arm. The article describes in detail how the primary outpoint (cost to the national health system), and some secondary outpoints, will be collected. Discussion: An overall rate of return on investment (ROI) statistically significant 13.0% per annum with an associated benefit/cost ratio (BCR) of 6.3 is expected as the primary outcome of the “WeCare Generation” program. Our proposed model predicts a new medical paradigm aiming to empower new generations, with a strong return on economy and health.

Suggested Citation

  • Orlando Uccellini & Andrea Benlodi & Emanuele Caroppo & Loredana Cena & Gianluca Esposito & Isabel Fernandez & Maria Ghazanfar & Antonio Imbasciati & Francesco Longo & Marianna Mazza & Giuseppe Marano, 2022. "1000 Days: The “WeCare Generation” Program—The Ultimate Model for Improving Human Mental Health and Economics: The Study Protocol," IJERPH, MDPI, vol. 19(24), pages 1-11, December.
  • Handle: RePEc:gam:jijerp:v:19:y:2022:i:24:p:16741-:d:1002336
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    References listed on IDEAS

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    1. García, Jorge Luis & Heckman, James J. & Ronda, Victor, 2021. "The Lasting Effects of Early Childhood Education on Promoting the Skills and Social Mobility of Disadvantaged African Americans," IZA Discussion Papers 14575, Institute of Labor Economics (IZA).
    2. Doyle, Orla & Harmon, Colm P. & Heckman, James J. & Tremblay, Richard E., 2009. "Investing in early human development: Timing and economic efficiency," Economics & Human Biology, Elsevier, vol. 7(1), pages 1-6, March.
    3. Lotte C Houtepen & Jon Heron & Matthew J Suderman & Abigail Fraser & Catherine R Chittleborough & Laura D Howe, 2020. "Associations of adverse childhood experiences with educational attainment and adolescent health and the role of family and socioeconomic factors: A prospective cohort study in the UK," PLOS Medicine, Public Library of Science, vol. 17(3), pages 1-21, March.
    4. Jonathan Levy & Abraham Goldstein & Ruth Feldman, 2019. "The neural development of empathy is sensitive to caregiving and early trauma," Nature Communications, Nature, vol. 10(1), pages 1-10, December.
    5. James J. Heckman, 2008. "The Case for Investing in Disadvantaged Young Children," ifo DICE Report, ifo Institute - Leibniz Institute for Economic Research at the University of Munich, vol. 6(2), pages 3-8, 07.
    6. James J. Heckman & Dimitriy V. Masterov, 2007. "The Productivity Argument for Investing in Young Children," Review of Agricultural Economics, Agricultural and Applied Economics Association, vol. 29(3), pages 446-493.
    7. James Heckman & Rodrigo Pinto & Peter Savelyev, 2013. "Understanding the Mechanisms through Which an Influential Early Childhood Program Boosted Adult Outcomes," American Economic Review, American Economic Association, vol. 103(6), pages 2052-2086, October.
    8. James J. Heckman, 2008. "The Case for Investing in Disadvantaged Young Children," ifo DICE Report, ifo Institute - Leibniz Institute for Economic Research at the University of Munich, vol. 6(02), pages 3-8, July.
    9. Jorge Luis García & James J. Heckman & Duncan Ermini Leaf & María José Prados, 2020. "Quantifying the Life-Cycle Benefits of an Influential Early-Childhood Program," Journal of Political Economy, University of Chicago Press, vol. 128(7), pages 2502-2541.
    10. Emanuele Caroppo & Marianna Mazza & Alessandra Sannella & Giuseppe Marano & Carla Avallone & Angelo Emilio Claro & Delfina Janiri & Lorenzo Moccia & Luigi Janiri & Gabriele Sani, 2021. "Will Nothing Be the Same Again?: Changes in Lifestyle during COVID-19 Pandemic and Consequences on Mental Health," IJERPH, MDPI, vol. 18(16), pages 1-8, August.
    11. repec:ces:ifodic:v:6:y:2008:i:2:p:14567127 is not listed on IDEAS
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