Repeated measures proportional odds logistic regression analysis of ordinal score data in the statistical software package R
AbstractThe widely used proportional odds model is developed for correlated repeated ordinal score data, using a modified version of the generalized estimating equation (GEE) method for model fitting for a range of working correlation models. The algorithm developed estimates the correlation parameter, by minimizing the generalized variance of the regression parameters at each step of the fitting algorithm. Methods for parameter estimation are described for the widely used uniform and first-order autoregressive correlation models, for data potentially recorded at irregularly spaced time intervals. A full implementation of the algorithm (repolr) in the R statistical software package, that both tests the assumption of proportional odds and accommodates missing data, is described and applied to a clinical trial of post-operative treatment, after rupture of the Achilles tendon and a study of patient pain response after hip joint resurfacing.
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Bibliographic InfoArticle provided by Elsevier in its journal Computational Statistics & Data Analysis.
Volume (Year): 53 (2009)
Issue (Month): 3 (January)
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Web page: http://www.elsevier.com/locate/csda
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- P. J. Lindsey & J. Kaufmann, 2004. "Analysis of a longitudinal ordinal response clinical trial using dynamic models," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 53(3), pages 523-537.
- N. R. Parsons & R. N. Edmondson & S. G. Gilmour, 2006. "A generalized estimating equation method for fitting autocorrelated ordinal score data with an application in horticultural research," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 55(4), pages 507-524.
- Jokinen, Jukka, 2006. "Fast estimation algorithm for likelihood-based analysis of repeated categorical responses," Computational Statistics & Data Analysis, Elsevier, vol. 51(3), pages 1509-1522, December.
- Verwaeren, Jan & Waegeman, Willem & De Baets, Bernard, 2012. "Learning partial ordinal class memberships with kernel-based proportional odds models," Computational Statistics & Data Analysis, Elsevier, vol. 56(4), pages 928-942.
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