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Testing Equality in Ordinal Data with Repeated Measurements: A Model-Free Approach

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  • Lui Kung-Jong

    (San Diego State University)

Abstract

In randomized clinical trials, we often encounter ordinal categorical responses with repeated measurements. We propose a model-free approach with using the generalized odds ratio (GOR) to measure the relative treatment effect. We develop procedures for testing equality of treatment effects and derive interval estimators for the GOR. We further develop a simple procedure for testing the treatment-by-period interaction. To illustrate the use of test procedures and interval estimators developed here, we consider two real-life data sets, one studying the gender effect on pain scores on an ordinal scale after hip joint resurfacing surgeries, and the other investigating the effect of an active hypnotic drug in insomnia patients on ordinal categories of time to falling asleep.

Suggested Citation

  • Lui Kung-Jong, 2016. "Testing Equality in Ordinal Data with Repeated Measurements: A Model-Free Approach," The International Journal of Biostatistics, De Gruyter, vol. 12(2), pages 1-10, November.
    • Handle: RePEc:bpj:ijbist:v:12:y:2016:i:2:p:10:n:9
    DOI: 10.1515/ijb-2015-0075
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    References listed on IDEAS

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    1. Bartolucci F. & Forcina A., 2002. "Extended RC Association Models Allowing for Order Restrictions and Marginal Modeling," Journal of the American Statistical Association, American Statistical Association, vol. 97, pages 1192-1199, December.
    2. Bartolucci F. & Forcina A. & Dardanoni V., 2001. "Positive Quadrant Dependence and Marginal Modeling in Two-Way Tables With Ordered Margins," Journal of the American Statistical Association, American Statistical Association, vol. 96, pages 1497-1505, December.
    3. Parsons, Nick R. & Costa, Matthew L. & Achten, Juul & Stallard, Nigel, 2009. "Repeated measures proportional odds logistic regression analysis of ordinal score data in the statistical software package R," Computational Statistics & Data Analysis, Elsevier, vol. 53(3), pages 632-641, January.
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