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Finding the missing heritability of complex diseases

Citations

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Cited by:

  1. Celine A. Manigbas & Bharati Jadhav & Paras Garg & Mariya Shadrina & William Lee & Gabrielle Altman & Alejandro Martin-Trujillo & Andrew J. Sharp, 2024. "A phenome-wide association study of tandem repeat variation in 168,554 individuals from the UK Biobank," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
  2. Abbas Saad Alatrany & Wasiq Khan & Abir Hussain & Dhiya Al-Jumeily & for the Alzheimer’s Disease Neuroimaging Initiative, 2023. "Wide and deep learning based approaches for classification of Alzheimer’s disease using genome-wide association studies," PLOS ONE, Public Library of Science, vol. 18(5), pages 1-21, May.
  3. Lin Yuan & Chang-An Yuan & De-Shuang Huang, 2017. "FAACOSE: A Fast Adaptive Ant Colony Optimization Algorithm for Detecting SNP Epistasis," Complexity, Hindawi, vol. 2017, pages 1-10, September.
  4. Young Lee & Suyeon Park & Sanghoon Moon & Juyoung Lee & Robert C. Elston & Woojoo Lee & Sungho Won, 2014. "On the Analysis of a Repeated Measure Design in Genome-Wide Association Analysis," IJERPH, MDPI, vol. 11(12), pages 1-21, November.
  5. Bar Haim Y. & Booth James G. & Wells Martin T., 2012. "A Mixture-Model Approach for Parallel Testing for Unequal Variances," Statistical Applications in Genetics and Molecular Biology, De Gruyter, vol. 11(1), pages 1-21, January.
  6. repec:plo:pone00:0075350 is not listed on IDEAS
  7. repec:plo:pone00:0188566 is not listed on IDEAS
  8. Chang Lu & Jan Zaucha & Rihab Gam & Hai Fang & Smithers & Matt E. Oates & Miguel Bernabe-Rubio & James Williams & Natalie Zelenka & Arun Prasad Pandurangan & Himani Tandon & Hashem Shihab & Raju Kalai, 2023. "Hypothesis-free phenotype prediction within a genetics-first framework," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
  9. Noha Sharafeldin & Martha L. Slattery & Qi Liu & Conrado Franco-Villalobos & Bette J. Caan & John D. Potter & Yutaka Yasui, 2017. "Multiple Gene-Environment Interactions on the Angiogenesis Gene-Pathway Impact Rectal Cancer Risk and Survival," IJERPH, MDPI, vol. 14(10), pages 1-15, September.
  10. repec:plo:pgen00:1003258 is not listed on IDEAS
  11. Lorena Alonso & Ignasi Morán & Cecilia Salvoro & David Torrents, 2021. "In Search of Complex Disease Risk through Genome Wide Association Studies," Mathematics, MDPI, vol. 9(23), pages 1-26, November.
  12. Ilias Georgakopoulos-Soares & Chengyu Deng & Vikram Agarwal & Candace S. Y. Chan & Jingjing Zhao & Fumitaka Inoue & Nadav Ahituv, 2023. "Transcription factor binding site orientation and order are major drivers of gene regulatory activity," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
  13. Ian Barnett & Rajarshi Mukherjee & Xihong Lin, 2017. "The Generalized Higher Criticism for Testing SNP-Set Effects in Genetic Association Studies," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 112(517), pages 64-76, January.
  14. Meida Wang & Shuanglin Zhang & Qiuying Sha, 2022. "A computationally efficient clustering linear combination approach to jointly analyze multiple phenotypes for GWAS," PLOS ONE, Public Library of Science, vol. 17(4), pages 1-13, April.
  15. repec:plo:pone00:0046501 is not listed on IDEAS
  16. repec:plo:pone00:0037385 is not listed on IDEAS
  17. Lucas Alvizi & Diogo Nani & Luciano Abreu Brito & Gerson Shigeru Kobayashi & Maria Rita Passos-Bueno & Roberto Mayor, 2023. "Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene–environment interaction," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
  18. repec:plo:pgen00:1003520 is not listed on IDEAS
  19. repec:plo:pone00:0083057 is not listed on IDEAS
  20. repec:plo:pone00:0118701 is not listed on IDEAS
  21. repec:plo:pgen00:1004787 is not listed on IDEAS
  22. repec:plo:pone00:0042530 is not listed on IDEAS
  23. Zhuoran Xu & Quan Li & Luigi Marchionni & Kai Wang, 2023. "PhenoSV: interpretable phenotype-aware model for the prioritization of genes affected by structural variants," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
  24. Jennifer A. Smith & Wei Zhao & Kalyn Yasutake & Carmella August & Scott M. Ratliff & Jessica D. Faul & Eric Boerwinkle & Aravinda Chakravarti & Ana V. Diez Roux & Yan Gao & Michael E. Griswold & Gerar, 2017. "Gene-by-Psychosocial Factor Interactions Influence Diastolic Blood Pressure in European and African Ancestry Populations: Meta-Analysis of Four Cohort Studies," IJERPH, MDPI, vol. 14(12), pages 1-18, December.
  25. Oxley, Florence A.R. & Wilding, Kirsty & von Stumm, Sophie, 2024. "DNA and IQ: Big deal or much ado about nothing? – A meta-analysis," Intelligence, Elsevier, vol. 107(C).
  26. Hans Fredrik Sunde & Nikolai Haahjem Eftedal & Rosa Cheesman & Elizabeth C. Corfield & Thomas H. Kleppesto & Anne Caroline Seierstad & Eivind Ystrom & Espen Moen Eilertsen & Fartein Ask Torvik, 2024. "Genetic similarity between relatives provides evidence on the presence and history of assortative mating," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
  27. repec:plo:pone00:0027407 is not listed on IDEAS
  28. repec:plo:pgen00:1003608 is not listed on IDEAS
  29. Guo, Fangqi & Harris, Kathleen Mullan & Boardman, Jason D. & Robinette, Jennifer W., 2022. "Does crime trigger genetic risk for type 2 diabetes in young adults? A G x E interaction study using national data," Social Science & Medicine, Elsevier, vol. 313(C).
  30. repec:plo:pcbi00:1002600 is not listed on IDEAS
  31. Bingxin Zhao & Fei Zou, 2022. "On polygenic risk scores for complex traits prediction," Biometrics, The International Biometric Society, vol. 78(2), pages 499-511, June.
  32. von Stumm, Sophie & Kandaswamy, Radhika & Maxwell, Jessye, 2023. "Gene-environment interplay in early life cognitive development," Intelligence, Elsevier, vol. 98(C).
  33. Surina Singh & Ananyo Choudhury & Scott Hazelhurst & Nigel J. Crowther & Palwendé R. Boua & Hermann Sorgho & Godfred Agongo & Engelbert A. Nonterah & Lisa K. Micklesfield & Shane A. Norris & Isaac Kis, 2023. "Genome-wide association study meta-analysis of blood pressure traits and hypertension in sub-Saharan African populations: an AWI-Gen study," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
  34. repec:plo:pcbi00:1000954 is not listed on IDEAS
  35. Ting Fu & Kofi Amoah & Tracey W. Chan & Jae Hoon Bahn & Jae-Hyung Lee & Sari Terrazas & Rockie Chong & Sriram Kosuri & Xinshu Xiao, 2024. "Massively parallel screen uncovers many rare 3′ UTR variants regulating mRNA abundance of cancer driver genes," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
  36. Andrea R. Waksmunski & Yeunjoo E. Song & Tyler G. Kinzy & Reneé A. Laux & Jane Sewell & Denise Fuzzell & Sarada Fuzzell & Sherri Miller & Janey L. Wiggs & Louis R. Pasquale & Jonathan M. Skarie & Jona, 2021. "The GGLEAM Study: Understanding Glaucoma in the Ohio Amish," IJERPH, MDPI, vol. 18(4), pages 1-13, February.
  37. Zheng Xu & Song Yan & Shuai Yuan & Cong Wu & Sixia Chen & Zifang Guo & Yun Li, 2023. "Efficient Two-Stage Analysis for Complex Trait Association with Arbitrary Depth Sequencing Data," Stats, MDPI, vol. 6(1), pages 1-14, March.
  38. repec:plo:pone00:0070774 is not listed on IDEAS
  39. repec:plo:pone00:0201140 is not listed on IDEAS
  40. Margaret Sunitha Selvaraj & Xihao Li & Zilin Li & Akhil Pampana & David Y. Zhang & Joseph Park & Stella Aslibekyan & Joshua C. Bis & Jennifer A. Brody & Brian E. Cade & Lee-Ming Chuang & Ren-Hua Chung, 2022. "Whole genome sequence analysis of blood lipid levels in >66,000 individuals," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
  41. Remo Monti & Pia Rautenstrauch & Mahsa Ghanbari & Alva Rani James & Matthias Kirchler & Uwe Ohler & Stefan Konigorski & Christoph Lippert, 2022. "Identifying interpretable gene-biomarker associations with functionally informed kernel-based tests in 190,000 exomes," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
  42. repec:plo:pgen00:1001202 is not listed on IDEAS
  43. Jayshree Advani & Puja A. Mehta & Andrew R. Hamel & Sudeep Mehrotra & Christina Kiel & Tobias Strunz & Ximena Corso-Díaz & Madeline Kwicklis & Freekje Asten & Rinki Ratnapriya & Emily Y. Chew & Dena G, 2024. "QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
  44. Agnieszka Boroń & Małgorzata Śmiarowska & Anna Grzywacz & Krzysztof Chmielowiec & Jolanta Chmielowiec & Jolanta Masiak & Tomasz Pawłowski & Dariusz Larysz & Andrzej Ciechanowicz, 2022. "Association of Polymorphism within the Putative miRNA Target Site in the 3′UTR Region of the DRD2 Gene with Neuroticism in Patients with Substance Use Disorder," IJERPH, MDPI, vol. 19(16), pages 1-21, August.
  45. repec:plo:pone00:0068913 is not listed on IDEAS
  46. repec:plo:pgen00:1006573 is not listed on IDEAS
  47. Sahir R Bhatnagar & Yi Yang & Tianyuan Lu & Erwin Schurr & JC Loredo-Osti & Marie Forest & Karim Oualkacha & Celia M T Greenwood, 2020. "Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models," PLOS Genetics, Public Library of Science, vol. 16(5), pages 1-25, May.
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