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Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations
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- Yi Duan & Huikuan Chu & Katharina Brandl & Lu Jiang & Suling Zeng & Nairika Meshgin & Eleni Papachristoforou & Josepmaria Argemi & Beatriz G. Mendes & Yanhan Wang & Hua Su & Weizhong Sun & Cristina Ll, 2021. "CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease," Nature Communications, Nature, vol. 12(1), pages 1-11, December.
- Yunpei Xu & Shaokai Wang & Qilong Feng & Jiazhi Xia & Yaohang Li & Hong-Dong Li & Jianxin Wang, 2024. "scCAD: Cluster decomposition-based anomaly detection for rare cell identification in single-cell expression data," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
- Stella Amanda & Tze King Tan & Jolynn Zu Lin Ong & Madelaine Skolastika Theardy & Regina Wan Ju Wong & Xiao Zi Huang & Muhammad Zulfaqar Ali & Yan Li & Zhiyuan Gong & Hiroshi Inagaki & Ee Yong Foo & B, 2022. "IRF4 drives clonal evolution and lineage choice in a zebrafish model of T-cell lymphoma," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
- T. Hautz & S. Salcher & M. Fodor & G. Sturm & S. Ebner & A. Mair & M. Trebo & G. Untergasser & S. Sopper & B. Cardini & A. Martowicz & J. Hofmann & S. Daum & M. Kalb & T. Resch & F. Krendl & A. Weisse, 2023. "Immune cell dynamics deconvoluted by single-cell RNA sequencing in normothermic machine perfusion of the liver," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
- Anna Podleśny-Drabiniok & Gloriia Novikova & Yiyuan Liu & Josefine Dunst & Rose Temizer & Chiara Giannarelli & Samuele Marro & Taras Kreslavsky & Edoardo Marcora & Alison Mary Goate, 2024. "BHLHE40/41 regulate microglia and peripheral macrophage responses associated with Alzheimer’s disease and other disorders of lipid-rich tissues," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
- Delilah Hendriks & Benedetta Artegiani & Thanasis Margaritis & Iris Zoutendijk & Susana Chuva de Sousa Lopes & Hans Clevers, 2024. "Mapping of mitogen and metabolic sensitivity in organoids defines requirements for human hepatocyte growth," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
- Delaram Pouyabahar & Tallulah Andrews & Gary D. Bader, 2025. "Interpretable single-cell factor decomposition using sciRED," Nature Communications, Nature, vol. 16(1), pages 1-16, December.
- Shufen Zheng & Philip S. Tsao & Cuiping Pan, 2024. "Abdominal aortic aneurysm and cardiometabolic traits share strong genetic susceptibility to lipid metabolism and inflammation," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
- Hongru Hu & Gerald Quon, 2024. "scPair: Boosting single cell multimodal analysis by leveraging implicit feature selection and single cell atlases," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
- Jujiao Kang & Yue-Ting Deng & Bang-Sheng Wu & Wei-Shi Liu & Ze-Yu Li & Shitong Xiang & Liu Yang & Jia You & Xiaohong Gong & Tianye Jia & Jin-Tai Yu & Wei Cheng & Jianfeng Feng, 2024. "Whole exome sequencing analysis identifies genes for alcohol consumption," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
- Ting Dong & Guangan Hu & Zhongqi Fan & Huirui Wang & Yinghui Gao & Sisi Wang & Hao Xu & Michael B. Yaffe & Matthew G. Vander Heiden & Guoyue Lv & Jianzhu Chen, 2024. "Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
- Mina Ogawa & Jia-Xin Jiang & Sunny Xia & Donghe Yang & Avrilynn Ding & Onofrio Laselva & Marcela Hernandez & Changyi Cui & Yuichiro Higuchi & Hiroshi Suemizu & Craig Dorrell & Markus Grompe & Christin, 2021. "Generation of functional ciliated cholangiocytes from human pluripotent stem cells," Nature Communications, Nature, vol. 12(1), pages 1-19, December.
- Yuanyuan Wei & Beidi Lan & Tao Zheng & Lin Yang & Xiaoxia Zhang & Lele Cheng & Gulinigaer Tuerhongjiang & Zuyi Yuan & Yue Wu, 2023. "GSDME-mediated pyroptosis promotes the progression and associated inflammation of atherosclerosis," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
- Franziska Hildebrandt & Alma Andersson & Sami Saarenpää & Ludvig Larsson & Noémi Van Hul & Sachie Kanatani & Jan Masek & Ewa Ellis & Antonio Barragan & Annelie Mollbrink & Emma R. Andersson & Joakim L, 2021. "Spatial Transcriptomics to define transcriptional patterns of zonation and structural components in the mouse liver," Nature Communications, Nature, vol. 12(1), pages 1-14, December.
- Zhilong Lin & Xiaofei Liu & Houwei Wang & Shumin Li & Ziqiang Miao & Jing Yang & Yuting Zhang & Kai Lei & Yifan Wu & Youmei Kang & Ruoyin Zheng & Zonglin Xie & Yixi Wen & Xiaoxue Ren & Chunxiao Liu & , 2025. "Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma," Nature Communications, Nature, vol. 16(1), pages 1-20, December.
- Mark A. Sanborn & Xinge Wang & Shang Gao & Yang Dai & Jalees Rehman, 2025. "Unveiling the cell-type-specific landscape of cellular senescence through single-cell transcriptomics using SenePy," Nature Communications, Nature, vol. 16(1), pages 1-19, December.
- David Requena & Jack A. Medico & Luis F. Soto-Ugaldi & Mahsa Shirani & James A. Saltsman & Michael S. Torbenson & Philip Coffino & Sanford M. Simon, 2024. "Liver cancer multiomics reveals diverse protein kinase A disruptions convergently produce fibrolamellar hepatocellular carcinoma," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
- Arashdeep Singh & Arati Rajeevan & Vishaka Gopalan & Piyush Agrawal & Chi-Ping Day & Sridhar Hannenhalli, 2022. "Broad misappropriation of developmental splicing profile by cancer in multiple organs," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
- Agnieska Brazovskaja & Tomás Gomes & Rene Holtackers & Philipp Wahle & Christiane Körner & Zhisong He & Theresa Schaffer & Julian Connor Eckel & René Hänsel & Malgorzata Santel & Makiko Seimiya & Timm, 2024. "Cell atlas of the regenerating human liver after portal vein embolization," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
- Brianna R. Watson & Biplab Paul & Raza Ur Rahman & Liat Amir-Zilberstein & Åsa Segerstolpe & Eliana T. Epstein & Shane Murphy & Ludwig Geistlinger & Tyrone Lee & Angela Shih & Jacques Deguine & Ramnik, 2025. "Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolution," Nature Communications, Nature, vol. 16(1), pages 1-16, December.
- Sarah Cappuyns & Gino Philips & Vincent Vandecaveye & Bram Boeckx & Rogier Schepers & Thomas Van Brussel & Ingrid Arijs & Aurelie Mechels & Ayse Bassez & Francesca Lodi & Joris Jaekers & Halit Topal &, 2023. "PD-1- CD45RA+ effector-memory CD8 T cells and CXCL10+ macrophages are associated with response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
- Jie Fang & Shivendra Singh & Changde Cheng & Sivaraman Natarajan & Heather Sheppard & Ahmed Abu-Zaid & Adam D. Durbin & Ha Won Lee & Qiong Wu & Jacob Steele & Jon P. Connelly & Hongjian Jin & Wenan Ch, 2023. "Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma," Nature Communications, Nature, vol. 14(1), pages 1-27, December.
- Shuo Feng & Liangfeng Huang & Anna Vathrakokoili Pournara & Ziliang Huang & Xinlu Yang & Yongjian Zhang & Alvis Brazma & Ming Shi & Irene Papatheodorou & Zhichao Miao, 2024. "Alleviating batch effects in cell type deconvolution with SCCAF-D," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
- Kodihalli C. Ravindra & Vishal S. Vaidya & Zhenyu Wang & Joel D. Federspiel & Richard Virgen-Slane & Robert A. Everley & Jane I. Grove & Camilla Stephens & Mireia F. Ocana & Mercedes Robles-Díaz & M. , 2023. "Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
- Lei Xiong & Kang Tian & Yuzhe Li & Weixi Ning & Xin Gao & Qiangfeng Cliff Zhang, 2022. "Online single-cell data integration through projecting heterogeneous datasets into a common cell-embedding space," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
- Taghreed Hirz & Shenglin Mei & Hirak Sarkar & Youmna Kfoury & Shulin Wu & Bronte M. Verhoeven & Alexander O. Subtelny & Dimitar V. Zlatev & Matthew W. Wszolek & Keyan Salari & Evan Murray & Fei Chen &, 2023. "Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses," Nature Communications, Nature, vol. 14(1), pages 1-20, December.