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Mitochondrial TCA cycle metabolites control physiology and disease
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- Shubhi Srivastava & Priyanka Gajwani & Jordan Jousma & Hiroe Miyamoto & Youjeong Kwon & Arundhati Jana & Peter T. Toth & Gege Yan & Sang-Ging Ong & Jalees Rehman, 2023. "Nuclear translocation of mitochondrial dehydrogenases as an adaptive cardioprotective mechanism," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
- Ayşegül Erdem & Silvia Marin & Diego A. Pereira-Martins & Marjan Geugien & Alan Cunningham & Maurien G. Pruis & Isabel Weinhäuser & Albert Gerding & Barbara M. Bakker & Albertus T. J. Wierenga & Eduar, 2022. "Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
- Le Tran Phuc Khoa & Wentao Yang & Mengrou Shan & Li Zhang & Fengbiao Mao & Bo Zhou & Qiang Li & Rebecca Malcore & Clair Harris & Lili Zhao & Rajesh C. Rao & Shigeki Iwase & Sundeep Kalantry & Stephani, 2024. "Quiescence enables unrestricted cell fate in naive embryonic stem cells," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
- Cesare Granata & Nikeisha J. Caruana & Javier Botella & Nicholas A. Jamnick & Kevin Huynh & Jujiao Kuang & Hans A. Janssen & Boris Reljic & Natalie A. Mellett & Adrienne Laskowski & Tegan L. Stait & A, 2021. "High-intensity training induces non-stoichiometric changes in the mitochondrial proteome of human skeletal muscle without reorganisation of respiratory chain content," Nature Communications, Nature, vol. 12(1), pages 1-18, December.
- Eunah Kim & Andrea Annibal & Yujin Lee & Hae-Eun H. Park & Seokjin Ham & Dae-Eun Jeong & Younghun Kim & Sangsoon Park & Sujeong Kwon & Yoonji Jung & JiSoo Park & Sieun S. Kim & Adam Antebi & Seung-Jae, 2023. "Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
- Tao Zhang & Sarah E. Noll & Jesus T. Peng & Amman Klair & Abigail Tripka & Nathan Stutzman & Casey Cheng & Richard N. Zare & Alexandra J. Dickinson, 2023. "Chemical imaging reveals diverse functions of tricarboxylic acid metabolites in root growth and development," Nature Communications, Nature, vol. 14(1), pages 1-12, December.
- Kai Shen & Hao Zhou & Qiang Zuo & Yue Gu & Jiangqi Cheng & Kai Yan & Huiwen Zhang & Huanghe Song & Wenwei Liang & Jinchun Zhou & Jiuxiang Liu & Feng Liu & Chenjun Zhai & Weimin Fan, 2024. "GATD3A-deficiency-induced mitochondrial dysfunction facilitates senescence of fibroblast-like synoviocytes and osteoarthritis progression," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
- Soeun Kang & Maciek R. Antoniewicz & Nissim Hay, 2024. "Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
- Greta Ehlers & Annika Marie Tödtmann & Lisa Holsten & Maike Willers & Julia Heckmann & Jennifer Schöning & Maximilian Richter & Anna Sophie Heinemann & Sabine Pirr & Alexander Heinz & Christian Dopfer, 2025. "Oxidative phosphorylation is a key feature of neonatal monocyte immunometabolism promoting myeloid differentiation after birth," Nature Communications, Nature, vol. 16(1), pages 1-20, December.
- Delfina Larrea & Kirstin A. Tamucci & Khushbu Kabra & Kevin R. Velasco & Taekyung D. Yun & Marta Pera & Jorge Montesinos & Rishi R. Agrawal & Carmen Paradas & John W. Smerdon & Emily R. Lowry & Anna S, 2025. "Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS)," Nature Communications, Nature, vol. 16(1), pages 1-20, December.
- Chujiao Lin & Qiyuan Yang & Dongsheng Guo & Jun Xie & Yeon-Suk Yang & Sachin Chaugule & Ngoc DeSouza & Won-Taek Oh & Rui Li & Zhihao Chen & Aijaz A. John & Qiang Qiu & Lihua Julie Zhu & Matthew B. Gre, 2022. "Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
- Davide G. Franchina & Henry Kurniawan & Melanie Grusdat & Carole Binsfeld & Luana Guerra & Lynn Bonetti & Leticia Soriano-Baguet & Anouk Ewen & Takumi Kobayashi & Sophie Farinelle & Anna Rita Minafra , 2022. "Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells," Nature Communications, Nature, vol. 13(1), pages 1-21, December.
- Debasmita Bhattacharya & Vicky Shah & Oreoluwa Oresajo & Anthony Scimè, 2021. "p107 mediated mitochondrial function controls muscle stem cell proliferative fates," Nature Communications, Nature, vol. 12(1), pages 1-17, December.
- Khanyisile Kgoadi & Prashant Bajpai & Chris C. Ibegbu & Hedwin Kitdorlang Dkhar & Ana Beatriz Enriquez & Stanzin Dawa & Sushma K. Cribbs & Jyothi Rengarajan, 2025. "Alveolar macrophages from persons with HIV mount impaired TNF signaling networks to M. tuberculosis infection," Nature Communications, Nature, vol. 16(1), pages 1-20, December.
- Haifeng Zhang & Busu Li & Qunhua Huang & Francesc López-Giráldez & Yoshiaki Tanaka & Qun Lin & Sameet Mehta & Guilin Wang & Morven Graham & Xinran Liu & In-Hyun Park & Anne Eichmann & Wang Min & Jenny, 2022. "Mitochondrial dysfunction induces ALK5-SMAD2-mediated hypovascularization and arteriovenous malformations in mouse retinas," Nature Communications, Nature, vol. 13(1), pages 1-21, December.
- Benjamin P. Hurrell & Doumet Georges Helou & Emily Howard & Jacob D. Painter & Pedram Shafiei-Jahani & Arlene H. Sharpe & Omid Akbari, 2022. "PD-L2 controls peripherally induced regulatory T cells by maintaining metabolic activity and Foxp3 stability," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
- Rania El-Botty & Ludivine Morriset & Elodie Montaudon & Zakia Tariq & Anne Schnitzler & Marina Bacci & Nicla Lorito & Laura Sourd & Léa Huguet & Ahmed Dahmani & Pierre Painsec & Heloise Derrien & Soph, 2023. "Oxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
- Hao Wu & Xiufeng Zhao & Sophia M. Hochrein & Miriam Eckstein & Gabriela F. Gubert & Konrad Knöpper & Ana Maria Mansilla & Arman Öner & Remi Doucet-Ladevèze & Werner Schmitz & Bart Ghesquière & Sebasti, 2023. "Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
- Daehwa Youn & Boseon Kim & Dahee Jeong & Ju Yeon Lee & Seha Kim & Dulguun Sumberzul & Rehna Paula Ginting & Min-Woo Lee & Ju Hwan Song & Ye Seul Park & Yumin Kim & Chang-Myung Oh & Mihye Lee & Jun Cho, 2025. "Cross-talks between Metabolic and Translational Controls during Beige Adipocyte Differentiation," Nature Communications, Nature, vol. 16(1), pages 1-21, December.
- Eduardo H. Gilglioni & Ao Li & Wadsen St-Pierre-Wijckmans & Tzu-Keng Shen & Israel Pérez-Chávez & Garnik Hovhannisyan & Michela Lisjak & Javier Negueruela & Valerie Vandenbempt & Julia Bauzá-Martinez , 2024. "PTPRK regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity," Nature Communications, Nature, vol. 15(1), pages 1-22, December.
- Tuğçe Beyazay & Kendra S. Belthle & Christophe Farès & Martina Preiner & Joseph Moran & William F. Martin & Harun Tüysüz, 2023. "Ambient temperature CO2 fixation to pyruvate and subsequently to citramalate over iron and nickel nanoparticles," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
- Lanqi Gong & Jie Luo & Yu Zhang & Yuma Yang & Shanshan Li & Xiaona Fang & Baifeng Zhang & Jiao Huang & Larry Ka-Yue Chow & Dittman Chung & Jinlin Huang & Cuicui Huang & Qin Liu & Lu Bai & Yuen Chak Ti, 2023. "Nasopharyngeal carcinoma cells promote regulatory T cell development and suppressive activity via CD70-CD27 interaction," Nature Communications, Nature, vol. 14(1), pages 1-24, December.
- Zaher ElBeck & Mohammad Bakhtiar Hossain & Humam Siga & Nikolay Oskolkov & Fredrik Karlsson & Julia Lindgren & Anna Walentinsson & Dominique Koppenhöfer & Rebecca Jarvis & Roland Bürli & Tanguy Jamier, 2024. "Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner," Nature Communications, Nature, vol. 15(1), pages 1-23, December.
- Ryann M. Fame & Peter N. Kalugin & Boryana Petrova & Huixin Xu & Paul A. Soden & Frederick B. Shipley & Neil Dani & Bradford Grant & Aja Pragana & Joshua P. Head & Suhasini Gupta & Morgan L. Shannon &, 2023. "Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal resolution," Nature Communications, Nature, vol. 14(1), pages 1-20, December.
- Wennan Zhao & Xue Wang & Lifeng Han & Chunze Zhang & Chenxi Wang & Dexin Kong & Mingzhe Zhang & Tong Xu & Gen Li & Ge Hu & Jiahua Luo & Sook Wah Yee & Jia Yang & Andreas Stahl & Xin Chen & Youcai Zhan, 2024. "SLC13A3 is a major effector downstream of activated β-catenin in liver cancer pathogenesis," Nature Communications, Nature, vol. 15(1), pages 1-21, December.
- Fabiola Diniz & Nguyen Yen Nhi Ngo & Mariel Colon-Leyva & Francesca Edgington-Giordano & Sylvia Hilliard & Kevin Zwezdaryk & Jiao Liu & Samir S. El-Dahr & Giovane G. Tortelote, 2023. "Acetyl-CoA is a key molecule for nephron progenitor cell pool maintenance," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
- Marine Lanfranchi & Sozerko Yandiev & Géraldine Meyer-Dilhet & Salma Ellouze & Martijn Kerkhofs & Raphael Dos Reis & Audrey Garcia & Camille Blondet & Alizée Amar & Anita Kneppers & Hélène Polvèche & , 2024. "The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
- Jiali Lv & Chang Pan & Yuping Cai & Xinyue Han & Cheng Wang & Jingjing Ma & Jiaojiao Pang & Feng Xu & Shuo Wu & Tianzhang Kou & Fandong Ren & Zheng-Jiang Zhu & Tao Zhang & Jiali Wang & Yuguo Chen, 2024. "Plasma metabolomics reveals the shared and distinct metabolic disturbances associated with cardiovascular events in coronary artery disease," Nature Communications, Nature, vol. 15(1), pages 1-13, December.