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The Cross-Validated Adaptive Epsilon-Net Estimator

Author

Listed:
  • Mark van der Laan

    (Division of Biostatistics, School of Public Health, University of California, Berkeley)

  • Sandrine Dudoit

    (Division of Biostatistics, School of Public Health, University of California, Berkeley)

  • Aad van der Vaart

    (Dept. of Mathematics, Vrije Universitat, Amsterdam)

Abstract

Suppose that we observe a sample of independent and identically distributed realizations of a random variable. Assume that the parameter of interest can be defined as the minimizer, over a suitably defined parameter space, of the expectation (with respect to the distribution of the random variable) of a particular (loss) function of a candidate parameter value and the random variable. Examples of commonly used loss functions are the squared error loss function in regression and the negative log-density loss function in density estimation. Minimizing the empirical risk (i.e., the empirical mean of the loss function) over the entire parameter space typically results in ill-defined or too variable estimators of the parameter of interest (i.e., the risk minimizer for the true data generating distribution). In this article, we propose a cross-validated epsilon-net estimation methodology that covers a broad class of estimation problems, including multivariate outcome prediction and multivariate density estimation. An epsilon-net sieve of a subspace of the parameter space is defined as a collection of finite sets of points, the epsilon-nets indexed by epsilon, which approximate the subspace up till a resolution of epsilon. Given a collection of subspaces of the parameter space, one constructs an epsilon-net sieve for each of the subspaces. For each choice of subspace and each value of the resolution epsilon, one defines a candidate estimator as the minimizer of the empirical risk over the corresponding epsilon-net. The cross-validated epsilon-net estimator is then defined as the candidate estimator corresponding to the choice of subspace and epsilon-value minimizing the cross-validated empirical risk. We derive a finite sample inequality which proves that the proposed estimator achieves the adaptive optimal minimax rate of convergence, where the adaptivity is achieved by considering epsilon-net sieves for various subspaces. We also address the implementation of the cross-validated epsilon-net estimation procedure. In the context of a linear regression model, we present results of a preliminary simulation study comparing the cross-validated epsilon-net estimator to the cross-validated L^1-penalized least squares estimator (LASSO) and the least angle regression estimator (LARS). Finally, we discuss generalizations of the proposed estimation methodology to censored data structures.

Suggested Citation

  • Mark van der Laan & Sandrine Dudoit & Aad van der Vaart, 2004. "The Cross-Validated Adaptive Epsilon-Net Estimator," U.C. Berkeley Division of Biostatistics Working Paper Series 1141, Berkeley Electronic Press.
  • Handle: RePEc:bep:ucbbio:1141
    Note: oai:bepress.com:ucbbiostat-1141
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    References listed on IDEAS

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    1. Molinaro, Annette M. & Dudoit, Sandrine & van der Laan, M.J.Mark J., 2004. "Tree-based multivariate regression and density estimation with right-censored data," Journal of Multivariate Analysis, Elsevier, vol. 90(1), pages 154-177, July.
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    Citations

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    Cited by:

    1. Luedtke Alexander R. & van der Laan Mark J., 2016. "Super-Learning of an Optimal Dynamic Treatment Rule," The International Journal of Biostatistics, De Gruyter, vol. 12(1), pages 305-332, May.
    2. Petersen, Maya L. & Molinaro, Annette M. & Sinisi, Sandra E. & van der Laan, Mark J., 2007. "Cross-validated bagged learning," Journal of Multivariate Analysis, Elsevier, vol. 98(9), pages 1693-1704, October.
    3. Porter Kristin E. & Gruber Susan & van der Laan Mark J. & Sekhon Jasjeet S., 2011. "The Relative Performance of Targeted Maximum Likelihood Estimators," The International Journal of Biostatistics, De Gruyter, vol. 7(1), pages 1-34, August.
    4. Haight, Thaddeus J. & Wang, Yue & van der Laan, Mark J. & Tager, Ira B., 2010. "A cross-validation deletion-substitution-addition model selection algorithm: Application to marginal structural models," Computational Statistics & Data Analysis, Elsevier, vol. 54(12), pages 3080-3094, December.
    5. Ertefaie Ashkan & Asgharian Masoud & Stephens David A., 2018. "Variable Selection in Causal Inference using a Simultaneous Penalization Method," Journal of Causal Inference, De Gruyter, vol. 6(1), pages 1-16, March.

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