IDEAS home Printed from https://ideas.repec.org/c/boc/bocode/s458717.html
 

METAFRAG: Stata module to compute the fragility index for meta-analysis

Author

Listed:
  • Ariel Linden

    (Linden Consulting Group, LLC)

Programming Language

Stata

Abstract

metafrag is an application of the fragility index for single studies with a binary outcome (Walsh et al. 2014) to meta-analysis (Atal et al. 2019). The fragility index for meta-analysis is defined as the minimum number of patients from one or more trials included in the meta-analysis for which a modification of the event status (ie, changing events to non-events, or non-events to events) would change the statistical significance of the pooled treatment effect (Atal et al. 2019). As such, a fragility index score of zero indicates that no modification of the event status is necessary to elicit a non-statistically significant pooled treatment effect. Conversely, a large fragility index score indicates that many modifications to the event status are required to change a statistically significant pooled effect to non-significant (and thus, the results may be considered more robust). metafrag is a post estimation command for meta esize, thereby capitalizing on the comprehensive list of options available in official Stata's meta suite for computing effect sizes for binary outcomes.

Suggested Citation

  • Ariel Linden, 2019. "METAFRAG: Stata module to compute the fragility index for meta-analysis," Statistical Software Components S458717, Boston College Department of Economics, revised 18 Jul 2020.
    • Handle: RePEc:boc:bocode:s458717
    Note: This module should be installed from within Stata by typing "ssc install metafrag". The module is made available under terms of the GPL v3 (https://www.gnu.org/licenses/gpl-3.0.txt). Windows users should not attempt to download these files with a web browser.
    as

    Download full text from publisher

    File URL: http://fmwww.bc.edu/repec/bocode/m/metafrag.ado
    File Function: program code
    Download Restriction: no
    File URL: http://fmwww.bc.edu/repec/bocode/m/metafrag.sthlp
    File Function: help file
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:boc:bocode:s458717. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Christopher F Baum (email available below). General contact details of provider: https://edirc.repec.org/data/debocus.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.