IDEAS home Printed from https://ideas.repec.org/a/spr/scient/v98y2014i3d10.1007_s11192-013-1132-3.html
   My bibliography  Save this article

Alzheimer’s disease research in the future: bibliometric analysis of cholinesterase inhibitors from 1993 to 2012

Author

Listed:
  • Huaqi Chen

    (Taizhou University)

  • Yuehua Wan

    (Zhejiang University of Technology)

  • Shuian Jiang

    (Taizhou University)

  • Yanxia Cheng

    (Zhejiang University of Technology)

Abstract

In this study, the bibliometric study of cholinesterase inhibitors was used to find the trend of Alzheimer’s disease (AD) research and the order of drugs which was most tolerated or more effective in AD treatment. 4,982 articles and reviews from the Science Citation Index Expanded during 1993–2012 were analyzed. The main results were as follows: The publication of cholinesterase inhibitor research increased overall during 1993–2012. Chinese Academy of Science had most publications, University of California, San Diego and Hebrew University of Jerusalem won first place with the highest average citation per paper and the highest h-index respectively. Neurosciences, pharmacology and chemistry were “raising” subject categories in cholinesterase inhibitors research. With the comprehensive analysis of distribution and change of author keywords in two 10-year-time periods, it can be concluded as follows: (i) the order of drugs which was most tolerated or more effective in AD treatment might be donepezil, galantamine, rivastigmine, tacrine, memantine and huperzine A, and memantine attracted increasing interest recently and might be used more frequently now, especially for moderate to severe dementia. (ii) The pathogenesis of oxidative stress hypothesis attracted extensive attention. The interest to β-amyloid cascade hypothesis increased slightly but that of the cholinergic hypothesis decreased during the past decade. (iii) “Oxidative stress”, “β-amyloid”, “neuroprotection”, “memory” and “cognition” are the main orientations in the AD research in the future.

Suggested Citation

  • Huaqi Chen & Yuehua Wan & Shuian Jiang & Yanxia Cheng, 2014. "Alzheimer’s disease research in the future: bibliometric analysis of cholinesterase inhibitors from 1993 to 2012," Scientometrics, Springer;Akadémiai Kiadó, vol. 98(3), pages 1865-1877, March.
    • Handle: RePEc:spr:scient:v:98:y:2014:i:3:d:10.1007_s11192-013-1132-3
    DOI: 10.1007/s11192-013-1132-3
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1007/s11192-013-1132-3
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1007/s11192-013-1132-3?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Hang Wen & Yi Huang, 2012. "Trends and performance of oxidative stress research from 1991 to 2010," Scientometrics, Springer;Akadémiai Kiadó, vol. 91(1), pages 51-63, April.
    2. Jennifer Keiser & Jürg Utzinger, 2005. "Trends in the core literature on tropical medicine: a bibliometric analysis from 1952-2002," Scientometrics, Springer;Akadémiai Kiadó, vol. 62(3), pages 351-365, March.
    3. Ling-Li Li & Guohua Ding & Nan Feng & Ming-Huang Wang & Yuh-Shan Ho, 2009. "Global stem cell research trend: Bibliometric analysis as a tool for mapping of trends from 1991 to 2006," Scientometrics, Springer;Akadémiai Kiadó, vol. 80(1), pages 39-58, July.
    4. Kun-Yang Chuang & Ya-Li Huang & Yuh-Shan Ho, 2007. "A bibliometric and citation analysis of stroke-related research in Taiwan," Scientometrics, Springer;Akadémiai Kiadó, vol. 72(2), pages 201-212, August.
    5. K. K. Mueen Ahmed & B. M. Gupta, 2013. "India’s contribution on antioxidants: a bibliometric analysis, 2001–10," Scientometrics, Springer;Akadémiai Kiadó, vol. 94(2), pages 741-754, February.
    6. Yang Cao & Sixing Zhou & Guobin Wang, 2013. "A bibliometric analysis of global laparoscopy research trends during 1997–2011," Scientometrics, Springer;Akadémiai Kiadó, vol. 96(3), pages 717-730, September.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Chen, Huaqi & Ho, Yuh-Shan, 2015. "Highly cited articles in biomass research: A bibliometric analysis," Renewable and Sustainable Energy Reviews, Elsevier, vol. 49(C), pages 12-20.
    2. Chen, Hua-Qi & Wang, Xiuping & He, Li & Chen, Ping & Wan, Yuehua & Yang, Lingyun & Jiang, Shuian, 2016. "Chinese energy and fuels research priorities and trend: A bibliometric analysis," Renewable and Sustainable Energy Reviews, Elsevier, vol. 58(C), pages 966-975.
    3. Cheng Wang & Runhua Wu & Lili Deng & Yong Chen & Yingde Li & Yuehua Wan, 2020. "A Bibliometric Analysis on No-Show Research: Status, Hotspots, Trends and Outlook," Sustainability, MDPI, vol. 12(10), pages 1-17, May.
    4. Min Song & Go Eun Heo & Dahee Lee, 2015. "Identifying the landscape of Alzheimer’s disease research with network and content analysis," Scientometrics, Springer;Akadémiai Kiadó, vol. 102(1), pages 905-927, January.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. H. Martinez & A. Jaime & J. Camacho, 2012. "Relative absorptive capacity: a research profiling," Scientometrics, Springer;Akadémiai Kiadó, vol. 92(3), pages 657-674, September.
    2. Jiang Tan & Hui-Zhen Fu & Yuh-Shan Ho, 2014. "A bibliometric analysis of research on proteomics in Science Citation Index Expanded," Scientometrics, Springer;Akadémiai Kiadó, vol. 98(2), pages 1473-1490, February.
    3. Yaoyang, Xu & Boeing, Wiebke J., 2013. "Mapping biofuel field: A bibliometric evaluation of research output," Renewable and Sustainable Energy Reviews, Elsevier, vol. 28(C), pages 82-91.
    4. Bensi Dong & Guoqiang Xu & Xiang Luo & Yi Cai & Wei Gao, 2012. "A bibliometric analysis of solar power research from 1991 to 2010," Scientometrics, Springer;Akadémiai Kiadó, vol. 93(3), pages 1101-1117, December.
    5. Ling-Li Li & Guohua Ding & Nan Feng & Ming-Huang Wang & Yuh-Shan Ho, 2009. "Global stem cell research trend: Bibliometric analysis as a tool for mapping of trends from 1991 to 2006," Scientometrics, Springer;Akadémiai Kiadó, vol. 80(1), pages 39-58, July.
    6. Beibei Niu & Song Hong & Jiefei Yuan & Sha Peng & Zhen Wang & Xu Zhang, 2014. "Global trends in sediment-related research in earth science during 1992–2011: a bibliometric analysis," Scientometrics, Springer;Akadémiai Kiadó, vol. 98(1), pages 511-529, January.
    7. Amanda Augusta Fernandes & Cristina Adams & Luciana Gomes de Araujo & João Paulo Romanelli & João Paulo Bispo Santos & Ricardo Ribeiro Rodrigues, 2022. "Forest Landscape Restoration and Local Stakeholders: A Global Bibliometric Mapping Analysis," Sustainability, MDPI, vol. 14(23), pages 1-17, December.
    8. Lie Yang & Zhulei Chen & Ting Liu & Zhe Gong & Yingjian Yu & Jia Wang, 2013. "Global trends of solid waste research from 1997 to 2011 by using bibliometric analysis," Scientometrics, Springer;Akadémiai Kiadó, vol. 96(1), pages 133-146, July.
    9. Hang Wen & Yi Huang, 2012. "Trends and performance of oxidative stress research from 1991 to 2010," Scientometrics, Springer;Akadémiai Kiadó, vol. 91(1), pages 51-63, April.
    10. Jingqiu Liao & Yi Huang, 2014. "Global trend in aquatic ecosystem research from 1992 to 2011," Scientometrics, Springer;Akadémiai Kiadó, vol. 98(2), pages 1203-1219, February.
    11. Lie Yang & Houqing Guo & Huan Chen & Liuyang He & Tiantian Sun, 2018. "A Bibliometric Analysis Of Desalination Research During 1997-2012," Water Conservation & Management (WCM), Zibeline International Publishing, vol. 2(1), pages 18-23, January.
    12. Xianwen Wang & Zhi Wang & Shenmeng Xu, 2013. "Tracing scientist’s research trends realtimely," Scientometrics, Springer;Akadémiai Kiadó, vol. 95(2), pages 717-729, May.
    13. Yingjin Song & Ruiyi Li & Guanyi Chen & Beibei Yan & Lei Zhong & Yuxin Wang & Yihang Li & Jinlei Li & Yingxiu Zhang, 2021. "Bibliometric Analysis of Current Status on Bioremediation of Petroleum Contaminated Soils during 2000–2019," IJERPH, MDPI, vol. 18(16), pages 1-20, August.
    14. Lin Zhang & Ronald Rousseau & Wolfgang Glänzel, 2016. "Diversity of references as an indicator of the interdisciplinarity of journals: Taking similarity between subject fields into account," Journal of the Association for Information Science & Technology, Association for Information Science & Technology, vol. 67(5), pages 1257-1265, May.
    15. Maribel Vega-Arce & Gonzalo Salas & Gastón Núñez-Ulloa & Cristián Pinto-Cortez & Ivelisse Torres Fernandez & Yuh-Shan Ho, 2019. "Research performance and trends in child sexual abuse research: a Science Citation Index Expanded-based analysis," Scientometrics, Springer;Akadémiai Kiadó, vol. 121(3), pages 1505-1525, December.
    16. Miroslav Nedelchev, 2018. "Bibliometric Review of Corporate Governance Theories and Methods," Economic Studies journal, Bulgarian Academy of Sciences - Economic Research Institute, issue 4, pages 126-145.
    17. Minchul Lee & Min Song, 2020. "Incorporating citation impact into analysis of research trends," Scientometrics, Springer;Akadémiai Kiadó, vol. 124(2), pages 1191-1224, August.
    18. Sai Kranthi Vanga & Ashutosh Singh & Brinda Harish Vagadia & Vijaya Raghavan, 2015. "Global food allergy research trend: a bibliometric analysis," Scientometrics, Springer;Akadémiai Kiadó, vol. 105(1), pages 203-213, October.
    19. Yuh-Shan Ho, 2016. "Rebuttal to: Liu et al. “Progress in global parallel computing research: a bibliometric approach”, vol. 95, pp 967–983," Scientometrics, Springer;Akadémiai Kiadó, vol. 108(3), pages 1693-1694, September.
    20. Wei Gao & Yan Chen & Yong Liu & Huai-cheng Guo, 2015. "Scientometric analysis of phosphorus research in eutrophic lakes," Scientometrics, Springer;Akadémiai Kiadó, vol. 102(3), pages 1951-1964, March.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:scient:v:98:y:2014:i:3:d:10.1007_s11192-013-1132-3. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.