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The Impact of Provider Networks on the Co-Prescriptions of Interacting Drugs: A Claims-Based Analysis

Author

Listed:
  • Mei-Sing Ong

    (Boston Children’s Hospital
    Macquarie University
    Harvard Medical School)

  • Karen L. Olson

    (Boston Children’s Hospital
    Harvard Medical School)

  • Laura Chadwick

    (Boston Children’s Hospital
    Harvard Medical School)

  • Chunfu Liu

    (HealthCore Inc.)

  • Kenneth D. Mandl

    (Boston Children’s Hospital
    Harvard Medical School
    Harvard Medical School)

Abstract

Introduction Multiple provider prescribing of interacting drugs is a preventable cause of morbidity and mortality, and fragmented care is a major contributing factor. We applied social network analysis to examine the impact of provider patient-sharing networks on the risk of multiple provider prescribing of interacting drugs. Methods We performed a retrospective analysis of commercial healthcare claims (years 2008–2011), including all non-elderly adult beneficiaries (n = 88,494) and their constellation of care providers. Patient-sharing networks were derived based on shared patients, and care constellation cohesion was quantified using care density, defined as the ratio between the total number of patients shared by provider pairs and the total number of provider pairs within the care constellation around each patient. Results In our study, 2% (n = 1796) of patients were co-prescribed interacting drugs by multiple providers. Multiple provider prescribing of interacting drugs was associated with care density (odds ratio per unit increase in the natural logarithm of the value for care density 0.78; 95% confidence interval 0.74–0.83; p

Suggested Citation

  • Mei-Sing Ong & Karen L. Olson & Laura Chadwick & Chunfu Liu & Kenneth D. Mandl, 2017. "The Impact of Provider Networks on the Co-Prescriptions of Interacting Drugs: A Claims-Based Analysis," Drug Safety, Springer, vol. 40(3), pages 263-272, March.
  • Handle: RePEc:spr:drugsa:v:40:y:2017:i:3:d:10.1007_s40264-016-0490-1
    DOI: 10.1007/s40264-016-0490-1
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    Cited by:

    1. Burns, Lawton R. & Nembhard, Ingrid M. & Shortell, Stephen M., 2022. "Integrating network theory into the study of integrated healthcare," Social Science & Medicine, Elsevier, vol. 296(C).

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