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With or without internal limiting membrane peeling during idiopathic epiretinal membrane surgery: A meta-analysis

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  • Qinying Huang
  • Jinying Li

Abstract

Background: Although previously published meta-analyses have compared the surgical effects between the methods of Idiopathic epiretinal membrane (iERM) removal with or without ILM peeling, they did not reach an agreement. Purpose: We aimed to provide more evidence for the treatment of iERM and whether additional ILM peeling was better or not by analyzing more updated studies and randomized control trials (RCTs). Method: The search was conducted in Pubmed, Embase, Cochrane Library, Web of Science and Open Grey without language limitation and the studies included were from inception to December 2019. All studies of iERM with or without ILM peeling showed at least one of outcomes, such as best-corrected visual acuity (BCVA), central macular thickness (CMT) and recurrence of ERM. The pooled results between above groups were showed by the mean differences (MDs) and risk ratios (RR) with corresponding 95% confidence intervals (CIs). Result: In total, 1645 eyes of five randomized controlled trials (RCTs) and fifteen retrospective studies were included. The short-term (

Suggested Citation

  • Qinying Huang & Jinying Li, 2021. "With or without internal limiting membrane peeling during idiopathic epiretinal membrane surgery: A meta-analysis," PLOS ONE, Public Library of Science, vol. 16(1), pages 1-15, January.
  • Handle: RePEc:plo:pone00:0245459
    DOI: 10.1371/journal.pone.0245459
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    References listed on IDEAS

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    1. Wei-Cheng Chang & Chin Lin & Cho-Hao Lee & Tzu-Ling Sung & Tao-Hsin Tung & Jorn-Hon Liu, 2017. "Vitrectomy with or without internal limiting membrane peeling for idiopathic epiretinal membrane: A meta-analysis," PLOS ONE, Public Library of Science, vol. 12(6), pages 1-18, June.
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