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Cognitive ability, education and socioeconomic status in childhood and risk of post-stroke depression in later life: A systematic review and meta-analysis

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  • Ellen V Backhouse
  • Caroline A McHutchison
  • Vera Cvoro
  • Susan D Shenkin
  • Joanna M Wardlaw

Abstract

Background: Depression after stroke is common and is associated with poorer recovery. Risk factors such as gender, age and stroke severity are established, but it is unclear whether factors from earlier in life might also contribute. Methods: We searched MEDLINE, PsycINFO, EMBASE and meta-analysed all available evidence on childhood (premorbid) IQ, socioeconomic status (SES), education and stroke in adulthood. We included all studies reporting data on >50 patients, calculating overall odds ratios (OR), mean difference, correlation, 95% confidence intervals (CI) and 95% predictive intervals (PI) using random effects methods. We quality assessed all studies, performed sensitivity analyses, assessed heterogeneity and publication bias. Results: We identified 33 studies including 2,664 participants with post-stroke depression and 5,460 without (314 participants not classified). Low education (

Suggested Citation

  • Ellen V Backhouse & Caroline A McHutchison & Vera Cvoro & Susan D Shenkin & Joanna M Wardlaw, 2018. "Cognitive ability, education and socioeconomic status in childhood and risk of post-stroke depression in later life: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 13(7), pages 1-15, July.
  • Handle: RePEc:plo:pone00:0200525
    DOI: 10.1371/journal.pone.0200525
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    Cited by:

    1. Fidel López-Espuela & Raúl Roncero-Martín & Maria de la Luz Canal-Macías & Jose M. Moran & Vicente Vera & Adela Gomez-Luque & Alejandro Lendinez-Mesa & Juan Diego Pedrera-Zamorano & Ignacio Casado-Nar, 2020. "Depressed Mood after Stroke: Predictive Factors at Six Months Follow-Up," IJERPH, MDPI, vol. 17(24), pages 1-11, December.
    2. Cave, Sophie Nicole & Wright, Megan & von Stumm, Sophie, 2022. "Change and stability in the association of parents' education with children's intelligence," Intelligence, Elsevier, vol. 90(C).
    3. Min-Woo Hong & Jong-Hwa Lee & Kyeong-Woo Lee & Sang-Beom Kim & Min-Gu Kang, 2021. "Risk Factors for Depressive Symptoms in Korean Adult Stroke Survivors: The Korea National Health and Nutrition Examination Survey IV–VII (2007–2018)," IJERPH, MDPI, vol. 18(15), pages 1-9, August.

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