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Depression Affects the Scores of All Facets of the WHOQOL-BREF and May Mediate the Effects of Physical Disability among Community-Dwelling Older Adults

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  • Yu-Chen Chang
  • Grace Yao
  • Susan C Hu
  • Jung-Der Wang

Abstract

Background: Geriatric depression is associated with the overall quality of life (QOL). However, how depressive symptoms affect the different domains and facets of QOL in older adults, and whether depressive symptoms mediate the relationship between physical disability and QOL in older adults are unclear. Methods: A total of 490 ambulatory community-dwelling older adults aged 65 years or above were interviewed using the brief version of the World Health Organisation Quality of Life instrument (WHOQOL-BREF), the Modified Barthel Index (MBI), the 15-item Geriatric Depression Scale (GDS-15), and the Mini-Mental State Examination (MMSE). Sequential models for multiple linear regressions were analysed to determine if the MBI, GDS-15 and MMSE scores predict the WHOQOL-BREF scores. The potential mediation effects of depression (as determined by the GDS-15) on the relationship between MBI and WHOQOL-BREF were also analysed. Results: The GDS-15 score was predictive of the scores of the four domains and all 26 facets of the WHOQOL-BREF. The significant predictive effects of the MBI score on 15 of the 26 facets of the WHOQOL-BREF were reduced to three after the adjustment for the GDS-15 score. Depression (as assessed by the GDS-15) is a mediator of the relationship between MBI and the physical, psychological and environmental domains of the WHOQOL-BREF. Conclusions: Depression (assessed by the GDS-15) may affect the scores of every domain and all facets of the WHOQOL-BREF in the elderly. Furthermore, it may mediate the relationship between the MBI and on QOL scores. We recommend taking depressive symptoms into consideration when measuring community-dwelling older adults’ QOL and providing active ageing programs.

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  • Yu-Chen Chang & Grace Yao & Susan C Hu & Jung-Der Wang, 2015. "Depression Affects the Scores of All Facets of the WHOQOL-BREF and May Mediate the Effects of Physical Disability among Community-Dwelling Older Adults," PLOS ONE, Public Library of Science, vol. 10(5), pages 1-11, May.
    • Handle: RePEc:plo:pone00:0128356
    DOI: 10.1371/journal.pone.0128356
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    References listed on IDEAS

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    1. Noe Garin & Beatriz Olaya & Maria Victoria Moneta & Marta Miret & Antonio Lobo & Jose Luis Ayuso-Mateos & Josep Maria Haro, 2014. "Impact of Multimorbidity on Disability and Quality of Life in the Spanish Older Population," PLOS ONE, Public Library of Science, vol. 9(11), pages 1-12, November.
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    1. Ana Maseda & Laura Lorenzo-López & Trinidad Lorenzo & Clara Diego-Diez & Begoña Alonso-Búa & Rocío López-López & José C. Millán-Calenti, 2018. "Determinants of Quality of Life in Pre-Frail Older Adults According to Phenotypic Criteria: the VERISAUDE Study," Applied Research in Quality of Life, Springer;International Society for Quality-of-Life Studies, vol. 13(1), pages 119-136, March.
    2. Ying-Chen Chi & Chen-Long Wu & Hsiang-Te Liu, 2022. "Assessing Quality of Life with Community Dwelling Elderly Adults: A Mass Survey in Taiwan," IJERPH, MDPI, vol. 19(22), pages 1-14, November.
    3. Henok Getachew Tegegn & Daniel Asfaw Erku & Girum Sebsibe & Biruktawit Gizaw & Dawit Seifu & Masho Tigabe & Sewunet Admasu Belachew & Asnakew Achaw Ayele, 2019. "Medication-related quality of life among Ethiopian elderly patients with polypharmacy: A cross-sectional study in an Ethiopia university hospital," PLOS ONE, Public Library of Science, vol. 14(3), pages 1-12, March.

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