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Comparison of Long-Term Survival of Patients with Solitary Large Hepatocellular Carcinoma of BCLC Stage A after Liver Resection or Transarterial Chemoembolization: A Propensity Score Analysis

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  • Shao-Liang Zhu
  • Yang Ke
  • Yu-Chong Peng
  • Liang Ma
  • Hang Li
  • Le-Qun Li
  • Jian-Hong Zhong

Abstract

Background: The aim of this study was to compare the long-term outcome of patients with a solitary large (>5 cm) hepatocellular carcinoma (HCC) in Barcelona Clinic Liver Cancer (BCLC) stage A who received liver resection (LR) or transarterial chemoembolization (TACE). Methods: Our study examined 128 patients treated by LR and 90 treated by TACE. To reduce bias in patient selection, we conducted propensity score analysis in the present study and 54 pairs of patients after propensity score matching were generated, their long-term survival was compared using the Kaplan–Meier method. Independent predictors of survival were identified by multivariate analysis. Results: Long-term survival was significantly better for the LR group by log-rank test (P

Suggested Citation

  • Shao-Liang Zhu & Yang Ke & Yu-Chong Peng & Liang Ma & Hang Li & Le-Qun Li & Jian-Hong Zhong, 2014. "Comparison of Long-Term Survival of Patients with Solitary Large Hepatocellular Carcinoma of BCLC Stage A after Liver Resection or Transarterial Chemoembolization: A Propensity Score Analysis," PLOS ONE, Public Library of Science, vol. 9(12), pages 1-13, December.
    • Handle: RePEc:plo:pone00:0115834
    DOI: 10.1371/journal.pone.0115834
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    References listed on IDEAS

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    1. Jian-Hong Zhong & Bang-De Xiang & Wen-Feng Gong & Yang Ke & Qin-Guo Mo & Liang Ma & Xing Liu & Le-Qun Li, 2013. "Comparison of Long-Term Survival of Patients with BCLC Stage B Hepatocellular Carcinoma after Liver Resection or Transarterial Chemoembolization," PLOS ONE, Public Library of Science, vol. 8(7), pages 1-8, July.
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