IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0050041.html
   My bibliography  Save this article

Performance of Different Gastric Cancer Screening Methods in Korea: A Population-Based Study

Author

Listed:
  • Kui Son Choi
  • Jae Kwan Jun
  • Eun-Cheol Park
  • Sohee Park
  • Kyu Won Jung
  • Mi Ah Han
  • Il Ju Choi
  • Hoo-Yeon Lee

Abstract

Background: There is a lack of agreement on which gastric cancer screening method is the most effective in the general population. The present study compared the relative performance of upper-gastrointestinal series (UGIS) and endoscopy screening for gastric cancer. Methods: A population-based study was conducted using the National Cancer Screening Program (NCSP) database. We analyzed data on 2,690,731 men and women in Korea who underwent either UGIS or endoscopy screening for gastric cancer between January 1, 2002 and December 31, 2005. Final gastric cancer diagnosis was ascertained through linkage with the Korean Central Cancer Registry. We calculated positivity rate, gastric cancer detection rate, interval cancer rate, sensitivity, specificity, and positive predictive value of UGIS and endoscopy screening. Results: The positivity rates for UGIS and endoscopy screening were 39.7 and 42.1 per 1,000 screenings, respectively. Gastric cancer detection rates were 0.68 and 2.61 per 1,000 screenings, respectively. In total, 2,067 interval cancers occurred within 1 year of a negative UGIS screening result (rate, 1.17/1,000) and 1,083 after a negative endoscopy screening result (rate, 1.17/1,000). The sensitivity of UGIS and endoscopy screening to detect gastric cancer was 36.7 and 69.0%, respectively, and specificity was 96.1 and 96.0%. The sensitivity of endoscopy screening to detect localized gastric cancer was 65.7%, which was statistically significantly higher than that of UGIS screening. Conclusion: Overall, endoscopy performed better than UGIS in the NCSP for gastric cancer. Further evaluation of the impact of these screening methods should take into account the corresponding costs and reduction in mortality.

Suggested Citation

  • Kui Son Choi & Jae Kwan Jun & Eun-Cheol Park & Sohee Park & Kyu Won Jung & Mi Ah Han & Il Ju Choi & Hoo-Yeon Lee, 2012. "Performance of Different Gastric Cancer Screening Methods in Korea: A Population-Based Study," PLOS ONE, Public Library of Science, vol. 7(11), pages 1-8, November.
    • Handle: RePEc:plo:pone00:0050041
    DOI: 10.1371/journal.pone.0050041
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050041
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0050041&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0050041?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Ming-ming He & Wen-jing Wu & Feng Wang & Zhi-qiang Wang & Dong-sheng Zhang & Hui-yan Luo & Miao-zhen Qiu & Feng-hua Wang & Chao Ren & Zhao-lei Zeng & Rui-hua Xu, 2013. "S-1-Based Chemotherapy versus Capecitabine-Based Chemotherapy as First-Line Treatment for Advanced Gastric Carcinoma: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 8(12), pages 1-1, December.
    2. Chisato Hamashima & Michiko Shabana & Mikizo Okamoto & Yoneatsu Osaki & Takuji Kishimoto, 2015. "Survival Analysis of Patients with Interval Cancer Undergoing Gastric Cancer Screening by Endoscopy," PLOS ONE, Public Library of Science, vol. 10(5), pages 1-15, May.
    3. Clara Benedetta Conti & Stefano Agnesi & Miki Scaravaglio & Pietro Masseria & Marco Emilio Dinelli & Massimo Oldani & Fabio Uggeri, 2023. "Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment," IJERPH, MDPI, vol. 20(3), pages 1-21, January.
    4. Rachel Farber & Nehmat Houssami & Isabelle Barnes & Kevin McGeechan & Alexandra Barratt & Katy J. L. Bell, 2022. "Considerations for Evaluating the Introduction of New Cancer Screening Technology: Use of Interval Cancers to Assess Potential Benefits and Harms," IJERPH, MDPI, vol. 19(22), pages 1-17, November.
    5. Jung, Minsoo, 2015. "National Cancer Screening Programs and Evidence-Based Healthcare Policy in South Korea," Health Policy, Elsevier, vol. 119(1), pages 26-32.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0050041. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.