IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0046175.html
   My bibliography  Save this article

Timing Matters in Hip Fracture Surgery: Patients Operated within 48 Hours Have Better Outcomes. A Meta-Analysis and Meta-Regression of over 190,000 Patients

Author

Listed:
  • Lorenzo Moja
  • Alessandra Piatti
  • Valentina Pecoraro
  • Cristian Ricci
  • Gianni Virgili
  • Georgia Salanti
  • Luca Germagnoli
  • Alessandro Liberati
  • Giuseppe Banfi

Abstract

Background: To assess the relationship between surgical delay and mortality in elderly patients with hip fracture. Systematic review and meta-analysis of retrospective and prospective studies published from 1948 to 2011. Medline (from 1948), Embase (from 1974) and CINAHL (from 1982), and the Cochrane Library. Odds ratios (OR) and 95% confidence intervals for each study were extracted and pooled with a random effects model. Heterogeneity, publication bias, Bayesian analysis, and meta-regression analyses were done. Criteria for inclusion were retro- and prospective elderly population studies, patients with operated hip fractures, indication of timing of surgery and survival status. Methodology/Principal Findings: There were 35 independent studies, with 191,873 participants and 34,448 deaths. The majority considered a cut-off between 24 and 48 hours. Early hip surgery was associated with a lower risk of death (pooled odds ratio (OR) 0.74, 95% confidence interval (CI) 0.67 to 0.81; P

Suggested Citation

  • Lorenzo Moja & Alessandra Piatti & Valentina Pecoraro & Cristian Ricci & Gianni Virgili & Georgia Salanti & Luca Germagnoli & Alessandro Liberati & Giuseppe Banfi, 2012. "Timing Matters in Hip Fracture Surgery: Patients Operated within 48 Hours Have Better Outcomes. A Meta-Analysis and Meta-Regression of over 190,000 Patients," PLOS ONE, Public Library of Science, vol. 7(10), pages 1-13, October.
    • Handle: RePEc:plo:pone00:0046175
    DOI: 10.1371/journal.pone.0046175
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046175
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0046175&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0046175?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Simona Cohen-Kadosh & Zilla Sinuany-Stern, 2020. "Hip fracture surgery efficiency in Israeli hospitals via a network data envelopment analysis," Central European Journal of Operations Research, Springer;Slovak Society for Operations Research;Hungarian Operational Research Society;Czech Society for Operations Research;Österr. Gesellschaft für Operations Research (ÖGOR);Slovenian Society Informatika - Section for Operational Research;Croatian Operational Research Society, vol. 28(1), pages 251-277, March.
    2. Alberto Grassi & Luca Andriolo & Davide Golinelli & Dario Tedesco & Simona Rosa & Pasquale Gramegna & Jacopo Ciaffi & Riccardo Meliconi & Maria Paola Landini & Giuseppe Filardo & Maria Pia Fantini & S, 2021. "Higher 90-Day Mortality after Surgery for Hip Fractures in Patients with COVID-19: A Case–Control Study from a Single Center in Italy," IJERPH, MDPI, vol. 18(10), pages 1-13, May.
    3. Kuangguo Zhou & Danmei Xu & Yang Cao & Jue Wang & Yunfan Yang & Mei Huang, 2014. "C-MYC Aberrations as Prognostic Factors in Diffuse Large B-cell Lymphoma: A Meta-Analysis of Epidemiological Studies," PLOS ONE, Public Library of Science, vol. 9(4), pages 1-9, April.
    4. Gutacker, Nils & Siciliani, Luigi & Moscelli, Giuseppe & Gravelle, Hugh, 2016. "Choice of hospital: Which type of quality matters?," Journal of Health Economics, Elsevier, vol. 50(C), pages 230-246.
    5. Tarazona Santabalbina FJ & Belenguer Varea A & Avellana Zaragoza JA & Cuesta Peredó D & De la Camara JM & Sivera S, 2018. "Importance of Surgical Delay on Mortality in Patients with Hip Fracture - Mini-Review," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 3(4), pages 3502-3505, April.
    6. Federico Pennestrì & Sabrina Corbetta & Vittoria Favero & Giuseppe Banfi, 2019. "Fragility Fracture Prevention—Implementing a Fracture Liaison Service in a High Volume Orthopedic Hospital," IJERPH, MDPI, vol. 16(24), pages 1-11, December.
    7. Andrea Ciaccio, 2023. "The Impact of a Cost-containment Measure on the Quality of Regional Health Services in Italy: a Parametric and a Non-parametric Approach," Working Papers 2023: 24, Department of Economics, University of Venice "Ca' Foscari".

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0046175. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.