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User-experience testing of an evidence-to-decision framework for selecting essential medicines

Author

Listed:
  • Thomas Piggott
  • Lorenzo Moja
  • Carlos A Cuello Garcia
  • Elie A Akl
  • Rita Banzi
  • Benedikt Huttner
  • Tamara Kredo
  • John N Lavis
  • Holger J Schünemann

Abstract

Essential medicine lists (EMLs) are important medicine prioritization tools used by the World Health Organization (WHO) EML and over 130 countries. The criteria used by WHO’s Expert Committee on the Selection and Use of Essential Medicines has parallels to the GRADE Evidence-to-Decision (EtD) frameworks. In this study, we explored the EtD frameworks and a visual abstract as adjunctive tools to strengthen the integrate evidence and improve the transparency of decisions of EML applications. We conducted user-experience testing interviews of key EML stakeholders using Morville’s honeycomb model. Interviews explored multifaceted dimensions (e.g., usability) on two EML applications for the 2021 WHO EML–long-acting insulin analogues for diabetes and immune checkpoint inhibitors for lung cancer. Using a pre-determined coding framework and thematic analysis we iteratively improved both the EtD framework and the visual abstract. We coded the transcripts of 17 interviews with 13 respondents in 103 locations of the interview texts across all dimensions of the user-experience honeycomb. Respondents felt the EtD framework and visual abstract presented complementary useful and findable adjuncts to the traditional EML application. They felt this would increase transparency and efficiency in evidence assessed by EML committees. As EtD frameworks are also used in health practice guidelines, including those by the WHO, respondents articulated that the adoption of the EtD by EML applications represents a tangible mechanism to align EMLs and guidelines, decrease duplication of work and improve coordination. Improvements were made to clarify instructions for the EtD and visual abstract, and to refine the design and content included. ‘Availability’ was added as an additional criterion for EML applications to highlight this criterion in alignment with WHO EML criteria. EtD frameworks and visual abstracts present additional important tools to communicate evidence and support decision-criteria in EML applications, which have global health impact. Access to essential medicines is important for achieving universal health coverage, and the development of essential medicine lists should be as evidence-based and trustworthy as possible.

Suggested Citation

  • Thomas Piggott & Lorenzo Moja & Carlos A Cuello Garcia & Elie A Akl & Rita Banzi & Benedikt Huttner & Tamara Kredo & John N Lavis & Holger J Schünemann, 2024. "User-experience testing of an evidence-to-decision framework for selecting essential medicines," PLOS Global Public Health, Public Library of Science, vol. 4(1), pages 1-15, January.
    • Handle: RePEc:plo:pgph00:0002723
    DOI: 10.1371/journal.pgph.0002723
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    References listed on IDEAS

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    1. Elizabeth F Peacocke & Sonja L Myhre & Hakan Safaralilo Foss & Unni Gopinathan, 2022. "National adaptation and implementation of WHO Model List of Essential Medicines: A qualitative evidence synthesis," PLOS Medicine, Public Library of Science, vol. 19(3), pages 1-23, March.
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