IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v469y2011i7330d10.1038_nature09640.html
   My bibliography  Save this article

Atomic-level modelling of the HIV capsid

Author

Listed:
  • Owen Pornillos

    (University of Virginia School of Medicine
    The Scripps Research Institute)

  • Barbie K. Ganser-Pornillos

    (University of Virginia School of Medicine
    The Scripps Research Institute)

  • Mark Yeager

    (University of Virginia School of Medicine
    The Scripps Research Institute
    University of Virginia Health System)

Abstract

The HIV-1 capsid modelled at the atomic level The human immunodeficiency virus 1 (HIV-1) virion has a cone-shaped core composed of capsid proteins, which take either pentameric or hexameric form. Mark Yeager and colleagues had previously solved the crystal structure of the capsid hexamer. Now they provide the structure of the pentamer, which allows them to propose the first atomic-level model of the mature HIV capsid.

Suggested Citation

  • Owen Pornillos & Barbie K. Ganser-Pornillos & Mark Yeager, 2011. "Atomic-level modelling of the HIV capsid," Nature, Nature, vol. 469(7330), pages 424-427, January.
    • Handle: RePEc:nat:nature:v:469:y:2011:i:7330:d:10.1038_nature09640
    DOI: 10.1038/nature09640
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature09640
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature09640?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Ahmed Abdul Quadeer & David Morales-Jimenez & Matthew R McKay, 2018. "Co-evolution networks of HIV/HCV are modular with direct association to structure and function," PLOS Computational Biology, Public Library of Science, vol. 14(9), pages 1-29, September.
    2. Hiroaki Takeuchi & Hideki Saito & Takeshi Noda & Tadashi Miyamoto & Tomokazu Yoshinaga & Kazutaka Terahara & Hiroshi Ishii & Yasuko Tsunetsugu-Yokota & Shoji Yamaoka, 2017. "Phosphorylation of the HIV-1 capsid by MELK triggers uncoating to promote viral cDNA synthesis," PLOS Pathogens, Public Library of Science, vol. 13(7), pages 1-35, July.
    3. Anna T. Gres & Karen A. Kirby & William M. McFadden & Haijuan Du & Dandan Liu & Chaoyi Xu & Alexander J. Bryer & Juan R. Perilla & Jiong Shi & Christopher Aiken & Xiaofeng Fu & Peijun Zhang & Ashwanth, 2023. "Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization," Nature Communications, Nature, vol. 14(1), pages 1-12, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:469:y:2011:i:7330:d:10.1038_nature09640. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.