IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v446y2007i7132d10.1038_nature05601.html
   My bibliography  Save this article

Hippocampal remapping and grid realignment in entorhinal cortex

Author

Listed:
  • Marianne Fyhn

    (Centre for the Biology of Memory, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway)

  • Torkel Hafting

    (Centre for the Biology of Memory, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway)

  • Alessandro Treves

    (Centre for the Biology of Memory, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway
    Cognitive Neuroscience Sector, SISSA International School for Advanced Studies, I-34014 Trieste, Italy)

  • May-Britt Moser

    (Centre for the Biology of Memory, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway)

  • Edvard I. Moser

    (Centre for the Biology of Memory, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway)

Abstract

A sense of place The ability to find one's way depends on the brain's ability to integrate information about location, direction and distance. Recent advances have pointed to 'grid cells' in the brain's entorhinal cortex as one component of the mechanism for calculating position, but the neuronal network computations responsible for spatial navigation and spatial memory formation are not understood. Experiments in rats tasked to track down their food in changing environments now reveal two distinct codes for memory representation in the hippocampus. The formation of statistically independent representations in hippocampal place cells ('remapping') is invariably preceded by a coherent migration of the corresponding ensemble maps in the entorhinal cortex. This allows an animal's position to be represented and updated by the same translation mechanism as it encounters different environments.

Suggested Citation

  • Marianne Fyhn & Torkel Hafting & Alessandro Treves & May-Britt Moser & Edvard I. Moser, 2007. "Hippocampal remapping and grid realignment in entorhinal cortex," Nature, Nature, vol. 446(7132), pages 190-194, March.
    • Handle: RePEc:nat:nature:v:446:y:2007:i:7132:d:10.1038_nature05601
    DOI: 10.1038/nature05601
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature05601
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature05601?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Torsten Neher & Amir Hossein Azizi & Sen Cheng, 2017. "From grid cells to place cells with realistic field sizes," PLOS ONE, Public Library of Science, vol. 12(7), pages 1-27, July.
    2. Isabella C. Wagner & Luise P. Graichen & Boryana Todorova & Andre Lüttig & David B. Omer & Matthias Stangl & Claus Lamm, 2023. "Entorhinal grid-like codes and time-locked network dynamics track others navigating through space," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
    3. Taylor J. Malone & Nai-Wen Tien & Yan Ma & Lian Cui & Shangru Lyu & Garret Wang & Duc Nguyen & Kai Zhang & Maxym V. Myroshnychenko & Jean Tyan & Joshua A. Gordon & David A. Kupferschmidt & Yi Gu, 2024. "A consistent map in the medial entorhinal cortex supports spatial memory," Nature Communications, Nature, vol. 15(1), pages 1-22, December.
    4. Benjamin Dunn & Maria Mørreaunet & Yasser Roudi, 2015. "Correlations and Functional Connections in a Population of Grid Cells," PLOS Computational Biology, Public Library of Science, vol. 11(2), pages 1-21, February.
    5. Francis Kei Masuda & Emily A. Aery Jones & Yanjun Sun & Lisa M. Giocomo, 2023. "Ketamine evoked disruption of entorhinal and hippocampal spatial maps," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
    6. Tiziano D’Albis & Richard Kempter, 2017. "A single-cell spiking model for the origin of grid-cell patterns," PLOS Computational Biology, Public Library of Science, vol. 13(10), pages 1-41, October.
    7. Lajos Vágó & Balázs B Ujfalussy, 2018. "Robust and efficient coding with grid cells," PLOS Computational Biology, Public Library of Science, vol. 14(1), pages 1-28, January.
    8. Trygve Solstad & Hosam N Yousif & Terrence J Sejnowski, 2014. "Place Cell Rate Remapping by CA3 Recurrent Collaterals," PLOS Computational Biology, Public Library of Science, vol. 10(6), pages 1-10, June.
    9. Axel Kammerer & Christian Leibold, 2014. "Hippocampal Remapping Is Constrained by Sparseness rather than Capacity," PLOS Computational Biology, Public Library of Science, vol. 10(12), pages 1-12, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:446:y:2007:i:7132:d:10.1038_nature05601. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.