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The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA

Author

Listed:
  • Qiaozhen Ye

    (Rice University)

  • Robert M. Krug

    (University of Texas at Austin)

  • Yizhi Jane Tao

    (Rice University)

Abstract

Groovy The structure of the influenza A virus nucleoprotein has proved elusive. But now its crystal structure has been determined, to reveal a crescent-shaped molecule containing connected head and body regions with a groove in between to accommodate the viral RNA. Now the contact points between this protein and other parts of the virus particle can be visualized, which should help in the development of antiviral therapeutics for influenza.

Suggested Citation

  • Qiaozhen Ye & Robert M. Krug & Yizhi Jane Tao, 2006. "The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA," Nature, Nature, vol. 444(7122), pages 1078-1082, December.
    • Handle: RePEc:nat:nature:v:444:y:2006:i:7122:d:10.1038_nature05379
    DOI: 10.1038/nature05379
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    Cited by:

    1. OSHO, Olayinka Kayode PhD, 2023. "Employee Loyalty And Organizational Performance," International Journal of Research and Innovation in Social Science, International Journal of Research and Innovation in Social Science (IJRISS), vol. 7(1), pages 552-567, January.

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