Author
Listed:
- Xiangchun Meng
(Yonsei University
Yonsei University)
- Xiao Xiao
(Yonsei University
Yonsei University)
- Sera Jeon
(Yonsei University
Yonsei University)
- Daniel Sanghyun Cho
(Sungkyunkwan University)
- Kejia Zhang
(Nanjing University of Science and Technology)
- Yong Hyun Kwon
(Yonsei University
Yonsei University)
- Hyeon Mo
(Yonsei University
Yonsei University)
- Yoojin Park
(Yonsei University
Yonsei University)
- Byung-Joon Park
(Yonsei University
Yonsei University)
- Dabin Kim
(Yonsei University
Yonsei University)
- Fengyi Pang
(Yonsei University
Yonsei University)
- SeongMin Kim
(Yonsei University
Yonsei University)
- Byung-Ok Choi
(Sungkyunkwan University School of Medicine
Samsung Medical Center
Samsung Advanced Institute for Health Sciences & Technology (SAIHST))
- Keren Dai
(Nanjing University of Science and Technology)
- Sang-Woo Kim
(Yonsei University
Yonsei University)
Abstract
Conventional wound closure techniques, such as suturing and stapling, often cause infection, delayed healing, and tissue damage, particularly in fragile or compromised tissues. A sutureless, battery-free adhesive strip (SBF strip) is developed to integrate shape-memory-assisted mechanical approximation with impedance-matched electrical stimulation for enhanced tissue repair. The device incorporates a shape memory polymer (SMP) responsive at near-body temperature and a robust wet-adhesive interface (> 200 J m−2), enabling rapid attachment and uniform closure under mild heating (40 °C). A built-in ultrasound-driven triboelectric system achieves optimal skin-impedance matching (~50 kΩ), generating electric fields up to 0.59 kV m−1 under 0.5 W cm−2 to promote cellular migration and proliferation. Finite element simulations reveal that SMP-induced contraction redistributes local mechanical strain, reducing scarring. In vivo rat studies demonstrate a 61.7% reduction in scar area compared to sutures, along with improved epithelial regeneration, collagen deposition, and angiogenesis. This mechanically and electrically synergistic platform offers a scalable, battery-free wound therapy strategy, reducing dependence on external power and disposable components while enabling precision-guided healing.
Suggested Citation
Xiangchun Meng & Xiao Xiao & Sera Jeon & Daniel Sanghyun Cho & Kejia Zhang & Yong Hyun Kwon & Hyeon Mo & Yoojin Park & Byung-Joon Park & Dabin Kim & Fengyi Pang & SeongMin Kim & Byung-Ok Choi & Keren , 2025.
"Self-contracting, battery-free triboelectric wound healing strip with strong wet adhesion,"
Nature Communications, Nature, vol. 16(1), pages 1-13, December.
Handle:
RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-025-62312-w
DOI: 10.1038/s41467-025-62312-w
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