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Several groups of LysM-RLKs are involved in symbiotic signal perception and arbuscular mycorrhiza establishment

Author

Listed:
  • Yi Ding

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Zélie Lesterps

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Virginie Gasciolli

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Anne-Laure Fuchs

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Mégane Gaston

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Lauréna Medioni

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Annélie de-Regibus

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Céline Remblière

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Céline Vicédo

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Sandra Bensmihen

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Jean Jacques Bono

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Julie Cullimore

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Guilhem Reyt

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

  • Marion Dalmais

    (Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2))

  • Christine Saffray

    (Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2))

  • Solène Mazeau

    (Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2))

  • Abdelhafid Bendahmane

    (Université Paris-Saclay, CNRS, INRAE, Univ Evry, Institute of Plant Sciences Paris-Saclay (IPS2))

  • Richard Sibout

    (INRAE, UR1268 BIA)

  • Michiel Vandenbussche

    (Univ Lyon, ENS de Lyon, UCB Lyon 1, CNRS, INRAE)

  • Jacques Rouster

    (Centre de Recherche de Chappes)

  • Tongming Wang

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS
    Southwest University)

  • Guanghua He

    (Southwest University)

  • Arnaud Masselin

    (Univ. Grenoble Alpes, CNRS, CERMAV)

  • Sylvain Cottaz

    (Univ. Grenoble Alpes, CNRS, CERMAV)

  • Sébastien Fort

    (Univ. Grenoble Alpes, CNRS, CERMAV)

  • Benoit Lefebvre

    (Laboratory of Plant-Microbe-Environment Interactions (LIPME), Université de Toulouse, INRAE, CNRS)

Abstract

Lipo-chitooligosaccharides (LCO) and short-chain chitooligosaccharides (CO) are produced by arbuscular mycorrhizal fungi (AMF) and activate the plant symbiosis signalling pathway, which is essential for mycorrhiza formation. High-affinity LCO receptors belonging to the LysM receptor-like kinase (LysM-RLK) phylogenetic group LYR-IA play a role in AM establishment, but it is unclear which proteins are the plant high-affinity short-chain CO receptors. Here we studied members of the uncharacterized LYR-IB group, and found that they show high affinity for LCO, short- and long-chain CO, and play a complementary role with the LYR-IA receptors for AM establishment. While LYR-IB knock out mutants had a reduced AMF colonization in several species, constitutive/ectopic expression in wheat increased AMF colonization. LYR-IB function is conserved in all tested angiosperms, but in most japonica rice a deletion creates a frameshift in the gene, explaining differences in AM phenotypes between rice and other monocot single LYR-IA mutants. In conclusion, we identified a class of LysM-RLK receptors in angiosperms with unique biochemical properties and a role in both LCO and CO perception for AM establishment.

Suggested Citation

  • Yi Ding & Zélie Lesterps & Virginie Gasciolli & Anne-Laure Fuchs & Mégane Gaston & Lauréna Medioni & Annélie de-Regibus & Céline Remblière & Céline Vicédo & Sandra Bensmihen & Jean Jacques Bono & Juli, 2025. "Several groups of LysM-RLKs are involved in symbiotic signal perception and arbuscular mycorrhiza establishment," Nature Communications, Nature, vol. 16(1), pages 1-14, December.
    • Handle: RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-025-60717-1
    DOI: 10.1038/s41467-025-60717-1
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    References listed on IDEAS

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    1. Xin-Ran Li & Jongho Sun & Doris Albinsky & Darius Zarrabian & Raphaella Hull & Tak Lee & Edwin Jarratt-Barnham & Chai Hao Chiu & Amy Jacobsen & Eleni Soumpourou & Alessio Albanese & Wouter Kohlen & Le, 2022. "Nutrient regulation of lipochitooligosaccharide recognition in plants via NSP1 and NSP2," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
    2. Fabienne Maillet & Véréna Poinsot & Olivier André & Virginie Puech-Pagès & Alexandra Haouy & Monique Gueunier & Laurence Cromer & Delphine Giraudet & Damien Formey & Andreas Niebel & Eduardo Andres Ma, 2011. "Fungal lipochitooligosaccharide symbiotic signals in arbuscular mycorrhiza," Nature, Nature, vol. 469(7328), pages 58-63, January.
    3. Feng Feng & Jongho Sun & Guru V. Radhakrishnan & Tak Lee & Zoltán Bozsóki & Sébastien Fort & Aleksander Gavrin & Kira Gysel & Mikkel B. Thygesen & Kasper Røjkjær Andersen & Simona Radutoiu & Jens Stou, 2019. "A combination of chitooligosaccharide and lipochitooligosaccharide recognition promotes arbuscular mycorrhizal associations in Medicago truncatula," Nature Communications, Nature, vol. 10(1), pages 1-12, December.
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