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A facile way to construct sensor array library via supramolecular chemistry for discriminating complex systems

Author

Listed:
  • Jia-Hong Tian

    (Nankai University)

  • Xin-Yue Hu

    (Nankai University)

  • Zong-Ying Hu

    (Nankai University)

  • Han-Wen Tian

    (Nankai University)

  • Juan-Juan Li

    (Nankai University)

  • Yu-Chen Pan

    (Nankai University)

  • Hua-Bin Li

    (Nankai University)

  • Dong-Sheng Guo

    (Nankai University)

Abstract

Differential sensing, which discriminates analytes via pattern recognition by sensor arrays, plays an important role in our understanding of many chemical and biological systems. However, it remains challenging to develop new methods to build a sensor unit library without incurring a high workload of synthesis. Herein, we propose a supramolecular approach to construct a sensor unit library by taking full advantage of recognition and assembly. Ten sensor arrays are developed by replacing the building block combinations, adjusting the ratio between system components, and changing the environment. Using proteins as model analytes, we examine the discriminative abilities of these supramolecular sensor arrays. Then the practical applicability for discriminating complex analytes is further demonstrated using honey as an example. This sensor array construction strategy is simple, tunable, and capable of developing many sensor units with as few syntheses as possible.

Suggested Citation

  • Jia-Hong Tian & Xin-Yue Hu & Zong-Ying Hu & Han-Wen Tian & Juan-Juan Li & Yu-Chen Pan & Hua-Bin Li & Dong-Sheng Guo, 2022. "A facile way to construct sensor array library via supramolecular chemistry for discriminating complex systems," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-31986-x
    DOI: 10.1038/s41467-022-31986-x
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    1. Mengwei Liu & Yujia Zhang & Jiachuang Wang & Nan Qin & Heng Yang & Ke Sun & Jie Hao & Lin Shu & Jiarui Liu & Qiang Chen & Pingping Zhang & Tiger H. Tao, 2022. "A star-nose-like tactile-olfactory bionic sensing array for robust object recognition in non-visual environments," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
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    Cited by:

    1. Jian-Shuang Guo & Juan-Juan Li & Ze-Han Wang & Yang Liu & Yu-Xin Yue & Hua-Bin Li & Xiu-He Zhao & Yuan-Jun Sun & Ya-Hui Ding & Fei Ding & Dong-Sheng Guo & Liang Wang & Yue Chen, 2023. "Dual hypoxia-responsive supramolecular complex for cancer target therapy," Nature Communications, Nature, vol. 14(1), pages 1-13, December.

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