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Comparative effectiveness and safety of homologous two-dose ChAdOx1 versus heterologous vaccination with ChAdOx1 and BNT162b2

Author

Listed:
  • Eduardo Hermosilla

    (Generalitat de Catalunya
    Universitat Autonoma de Barcelona)

  • Ermengol Coma

    (Generalitat de Catalunya)

  • Junqing Xie

    (University of Oxford)

  • Shuo Feng

    (University of Oxford)

  • Carmen Cabezas

    (Generalitat de Catalunya)

  • Leonardo Méndez-Boo

    (Generalitat de Catalunya)

  • Francesc Fina

    (Generalitat de Catalunya)

  • Elisabet Ballo

    (Generalitat de Catalunya)

  • Montserrat Martínez

    (Generalitat de Catalunya)

  • Manuel Medina-Peralta

    (Generalitat de Catalunya)

  • Josep Maria Argimon

    (Generalitat de Catalunya)

  • Daniel Prieto-Alhambra

    (University of Oxford
    Erasmus University Medical Center)

Abstract

Small trials have suggested that heterologous vaccination with first-dose ChAdOx1 and second-dose BNT162b2 may generate a better immune response than homologous vaccination with two doses of ChAdOx1. In this cohort analysis, we use linked data from Catalonia (Spain), where those aged

Suggested Citation

  • Eduardo Hermosilla & Ermengol Coma & Junqing Xie & Shuo Feng & Carmen Cabezas & Leonardo Méndez-Boo & Francesc Fina & Elisabet Ballo & Montserrat Martínez & Manuel Medina-Peralta & Josep Maria Argimon, 2022. "Comparative effectiveness and safety of homologous two-dose ChAdOx1 versus heterologous vaccination with ChAdOx1 and BNT162b2," Nature Communications, Nature, vol. 13(1), pages 1-7, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-29301-9
    DOI: 10.1038/s41467-022-29301-9
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    References listed on IDEAS

    as
    1. Maria Garcia-Gil & Josep-Maria Elorza & Marta Banque & Marc Comas-Cufí & Jordi Blanch & Rafel Ramos & Leonardo Méndez-Boo & Eduardo Hermosilla & Bonaventura Bolibar & Daniel Prieto-Alhambra, 2014. "Linking of Primary Care Records to Census Data to Study the Association between Socioeconomic Status and Cancer Incidence in Southern Europe: A Nation-Wide Ecological Study," PLOS ONE, Public Library of Science, vol. 9(10), pages 1-7, October.
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