IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i7p4242-d785756.html
   My bibliography  Save this article

Neurological and Mental Health Symptoms Associated with Post-COVID-19 Disability in a Sample of Patients Discharged from a COVID-19 Ward: A Secondary Analysis

Author

Listed:
  • Martina Cacciatore

    (Neurology, Public Health Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy)

  • Alberto Raggi

    (Neurology, Public Health Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy)

  • Andrea Pilotto

    (Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy)

  • Viviana Cristillo

    (Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy)

  • Erika Guastafierro

    (Neurology, Public Health Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy)

  • Claudia Toppo

    (Neurology, Public Health Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy)

  • Francesca G. Magnani

    (Neurology, Public Health Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy)

  • Davide Sattin

    (Neurology, Public Health Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy)

  • Arianna Mariniello

    (Neurology, Public Health Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy)

  • Fabiola Silvaggi

    (Neurology, Public Health Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy)

  • Stefano Cotti Piccinelli

    (Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy)

  • Nicola Zoppi

    (Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy)

  • Giulio Bonzi

    (Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy)

  • Stefano Gipponi

    (Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy)

  • Ilenia Libri

    (Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy)

  • Michela Bezzi

    (Respiratory Unit, ASST Spedali Civili di Brescia, 25121 Brescia, Italy)

  • Paolo Martelletti

    (Department of Clinical and Molecular Medicine, Sapienza University, 00185 Rome, Italy
    Regional Referral Headache Center, Sant’Andrea University Hospital, 00189 Rome, Italy)

  • Matilde Leonardi

    (Neurology, Public Health Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy)

  • Alessandro Padovani

    (Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, 25121 Brescia, Italy)

Abstract

Recent studies suggest that COVID-19 survivors may experience long-term health consequences: in particular, neurological and mental health symptoms might be associated with long-term negative outcomes. This study is a secondary analysis of a larger cohort study and aims to determine the extent to which neurological and mental health sequelae are associated with survivors’ disability. Participants include COVID-19 survivors, with no pre-morbid brain conditions, who were discharged from the COVID-19 Unit of the ASST Spedali Civili Hospital between February and April 2020. At an average of 3.5 months after discharge, they were submitted to a neurological examination and completed the WHO Disability Assessment Schedule (WHODAS-12), the Hospital Anxiety and Depression Score, the Pittsburgh Sleep Quality Index and the Montreal Cognitive Assessment. Multivariable regression analysis was carried out to analyze variables that explain WHODAS-12 variation. In total, 83 patients (63 males, average age 66.9, 95% CI: 64.2–69.7) were enrolled; average WHODAS-12 was 13.2 (95% CI: 9.7–16.6). Cognitive dysfunction, anxiety, fatigue, and hyposmia/hypogeusia explained 28.8% of WHODAS-12 variation. These findings underline the importance and need for longitudinal follow-up assessments after recovery from COVID-19 and suggest the need for early rehabilitation of residual symptoms to enhance patients’ functioning.

Suggested Citation

  • Martina Cacciatore & Alberto Raggi & Andrea Pilotto & Viviana Cristillo & Erika Guastafierro & Claudia Toppo & Francesca G. Magnani & Davide Sattin & Arianna Mariniello & Fabiola Silvaggi & Stefano Co, 2022. "Neurological and Mental Health Symptoms Associated with Post-COVID-19 Disability in a Sample of Patients Discharged from a COVID-19 Ward: A Secondary Analysis," IJERPH, MDPI, vol. 19(7), pages 1-10, April.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:7:p:4242-:d:785756
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/7/4242/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/7/4242/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Jeannet M. Delbressine & Felipe V. C. Machado & Yvonne M. J. Goërtz & Maarten Van Herck & Roy Meys & Sarah Houben-Wilke & Chris Burtin & Frits M. E. Franssen & Yvonne Spies & Herman Vijlbrief & Alex J, 2021. "The Impact of Post-COVID-19 Syndrome on Self-Reported Physical Activity," IJERPH, MDPI, vol. 18(11), pages 1-11, June.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Alessio Manfredini & Francesca Pisano & Chiara Incoccia & Paola Marangolo, 2023. "The Impact of COVID-19 Lockdown Measures and COVID-19 Infection on Cognitive Functions: A Review in Healthy and Neurological Populations," IJERPH, MDPI, vol. 20(6), pages 1-19, March.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. James Shelley & Joanne Hudson & Kelly A. Mackintosh & Zoe L. Saynor & Jamie Duckers & Keir E. Lewis & Gwyneth A. Davies & Ronan M. G. Berg & Melitta A. McNarry, 2021. "‘I Live a Kind of Shadow Life’: Individual Experiences of COVID-19 Recovery and the Impact on Physical Activity Levels," IJERPH, MDPI, vol. 18(21), pages 1-13, October.
    2. Armando Monterrosa Quintero & Ana Rita Echeverri Rios & Juan Pedro Fuentes-Garcia & Juan Carlos Gonzalez Sanchez, 2022. "Levels of Physical Activity and Psychological Well-Being in Non-Athletes and Martial Art Athletes during the COVID-19 Pandemic," IJERPH, MDPI, vol. 19(7), pages 1-14, March.
    3. Konstantin Warneke & Andreas Konrad & Michael Keiner & Astrid Zech & Masatoshi Nakamura & Martin Hillebrecht & David G. Behm, 2022. "Using Daily Stretching to Counteract Performance Decreases as a Result of Reduced Physical Activity—A Controlled Trial," IJERPH, MDPI, vol. 19(23), pages 1-14, November.
    4. Johanna Almgren & Emma Löfström & Julia S Malmborg & Jens Nygren & Johan Undén & Ingrid Larsson, 2022. "Patients’ Health Experiences of Post COVID-19 Condition—A Qualitative Study," IJERPH, MDPI, vol. 19(21), pages 1-12, October.
    5. Rafael Martínez-Gallego & Juan Pedro Fuentes-García & Miguel Crespo, 2021. "COVID-19 Prevention Measures Implemented by Tennis Coaches: The Role of Continent, Experience, and Type of Facility," IJERPH, MDPI, vol. 18(23), pages 1-12, December.
    6. Karolina Juszko & Patryk Szary & Justyna Mazurek & Sebastian Rutkowski & Błażej Cieślik & Joanna Szczepańska-Gieracha & Robert Gajda, 2022. "Long-Term Consequences of COVID-19 Disease Specific to Women: Exploratory Research," IJERPH, MDPI, vol. 20(1), pages 1-13, December.
    7. Isabel A. L. Slurink & Veerle R. Smaardijk & Willem J. Kop & Nina Kupper & Floortje Mols & Dounya Schoormans & Sabita S. Soedamah-Muthu, 2022. "Changes in Perceived Stress and Lifestyle Behaviors in Response to the COVID-19 Pandemic in The Netherlands: An Online Longitudinal Survey Study," IJERPH, MDPI, vol. 19(7), pages 1-13, April.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:7:p:4242-:d:785756. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.