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A Meta-Analysis of the Effects of Different Exercise Modes on Inflammatory Response in the Elderly

Author

Listed:
  • Haotian Zhao

    (Department of Physical Education, Jiangnan University, Wuxi 214122, China
    These authors contributed equally to this work.)

  • Zhijian He

    (Department of Sports Teaching and Research, Lanzhou University, Lanzhou 730000, China
    These authors contributed equally to this work.)

  • Hezhang Yun

    (School of Sport Science, Beijing Sport University, Beijing 100084, China
    These authors contributed equally to this work.)

  • Ruifu Wang

    (Department of Physical Education, Beijing Forestry University, Beijing 100083, China)

  • Chang Liu

    (School of Sport Science, Beijing Sport University, Beijing 100084, China)

Abstract

The aim of this study was to investigate the effects of different exercise modes on improving inflammatory response in the elderly. For the research methodology, databases such as CNKI (China National Knowledge Infrastructure), Wanfang Data, Pubmed, Web of Science, and EBSCO were selected for searching. The Cochrane Risk of Bias (ROB) tool was used to evaluate the methodological quality of the included studies, and RevMan5.4.1 analysis software was applied for the statistical analysis. A total of 31 studies (20 randomized controlled trials and 11 self-controlled trials) with 1528 subjects were included. The results of this meta-analysis showed that aerobic exercise, resistance exercise, aerobic + resistance exercise, and HIIT all significantly reduced the levels of IL-6, TNF-α, and CRP in the elderly, and the improvement effects of aerobic + resistance exercise on IL-6, HIIT on TNF-α, and resistance exercise on CRP in the elderly were better than those of the other three exercise modes, respectively. In conclusion, aerobic exercise, resistance exercise, aerobic + resistance exercise, and HIIT all contribute to ameliorating the inflammatory status of the elderly, among which resistance exercise is a noteworthy exercise mode for the elderly to improve inflammatory status.

Suggested Citation

  • Haotian Zhao & Zhijian He & Hezhang Yun & Ruifu Wang & Chang Liu, 2022. "A Meta-Analysis of the Effects of Different Exercise Modes on Inflammatory Response in the Elderly," IJERPH, MDPI, vol. 19(16), pages 1-13, August.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:16:p:10451-:d:894649
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    References listed on IDEAS

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    1. Sang-Dol Kim & Young-Ran Yeun, 2022. "Effects of Resistance Training on C-Reactive Protein and Inflammatory Cytokines in Elderly Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials," IJERPH, MDPI, vol. 19(6), pages 1-13, March.
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