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Cognitive Behavioral Therapy Program for Cannabis Use Cessation in First-Episode Psychosis Patients: A 1-Year Randomized Controlled Trial

Author

Listed:
  • Itxaso González-Ortega

    (Centre for Biomedical Research in the Mental Health Network (CIBERSAM), 28029 Madrid, Spain
    Bioaraba Research Institute, Department of Psychiatry, Araba University Hospital, 01004 Vitoria, Spain
    Department of Personality, Assessment and Psychological Treatment, National University of Distance Education (UNED), 01008 Vitoria, Spain)

  • Enrique Echeburúa

    (Centre for Biomedical Research in the Mental Health Network (CIBERSAM), 28029 Madrid, Spain
    Department of Personality, Assessment and Psychological Treatment, University of the Basque Country, Biodonostia, 20018 San Sebastian, Spain)

  • Susana Alberich

    (Centre for Biomedical Research in the Mental Health Network (CIBERSAM), 28029 Madrid, Spain
    Bioaraba Research Institute, Department of Psychiatry, Araba University Hospital, 01004 Vitoria, Spain
    Department of Fundamental Mathematics, National University of Distance Education (UNED), 01008 Vitoria, Spain)

  • Miguel Bernardo

    (Centre for Biomedical Research in the Mental Health Network (CIBERSAM), 28029 Madrid, Spain
    Department of Psychiatry, Hospital Clinic of Barcelona, Neuroscience Institute, University of Barcelona, 08036 Barcelona, Spain
    Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain)

  • Eduard Vieta

    (Centre for Biomedical Research in the Mental Health Network (CIBERSAM), 28029 Madrid, Spain
    Department of Psychiatry, Hospital Clinic of Barcelona, Neuroscience Institute, University of Barcelona, 08036 Barcelona, Spain
    Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain)

  • Gonzalo Salazar de Pablo

    (Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London SE5 8AB, UK
    Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London SE5 8AB, UK
    Child and Adolescent Mental Health Services, South London & Maudsley NHS Trust, London SE11 6JJ, UK)

  • Ana González-Pinto

    (Centre for Biomedical Research in the Mental Health Network (CIBERSAM), 28029 Madrid, Spain
    Bioaraba Research Institute, Department of Psychiatry, Araba University Hospital, 01004 Vitoria, Spain
    Department of Neurosciences, University of the Basque Country, 48940 Leioa, Spain)

Abstract

Despite the negative influence of cannabis use on the development and prognosis of first-episode psychosis (FEP), there is little evidence on effective specific interventions for cannabis use cessation in FEP. The aim of this study was to compare the efficacy of a specific cognitive behavioral therapy (CBT) for cannabis cessation (CBT-CC) with treatment as usual (TAU) in FEP cannabis users. In this single-blind, 1-year randomized controlled trial, 65 participants were randomly assigned to CBT-CC or TAU. The primary outcome was the reduction in cannabis use severity. The CBT-CC group had a greater decrease in cannabis use severity and positive psychotic symptoms over time, and a greater improvement in functioning at post-treatment than TAU. The treatment response was also faster in the CBT-CC group, reducing cannabis use, anxiety, positive and general psychotic symptoms, and improving functioning earlier than TAU in the follow-up. Moreover, patients who stopped and/or reduced cannabis use during the follow-up, decreased psychotic symptoms and increased awareness of disease compared to those who continued using cannabis. Early intervention based on a specific CBT for cannabis cessation, may be effective in reducing cannabis use severity, in addition to improving clinical and functional outcomes of FEP cannabis users.

Suggested Citation

  • Itxaso González-Ortega & Enrique Echeburúa & Susana Alberich & Miguel Bernardo & Eduard Vieta & Gonzalo Salazar de Pablo & Ana González-Pinto, 2022. "Cognitive Behavioral Therapy Program for Cannabis Use Cessation in First-Episode Psychosis Patients: A 1-Year Randomized Controlled Trial," IJERPH, MDPI, vol. 19(12), pages 1-19, June.
  • Handle: RePEc:gam:jijerp:v:19:y:2022:i:12:p:7325-:d:839177
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    References listed on IDEAS

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    1. Itxaso González-Ortega & Patricia Vega & Enrique Echeburúa & Susana Alberich & Jessica Fernández-Sevillano & Sara Barbeito & Vicent Balanzá-Martínez & Eduard Vieta & Esther Lorente-Rovira & Ana Luengo, 2021. "A Multicentre, Randomised, Controlled Trial of a Combined Clinical Treatment for First-Episode Psychosis," IJERPH, MDPI, vol. 18(14), pages 1-13, July.
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