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New Advances in Cervical Cancer: From Bench to Bedside

Author

Listed:
  • Ottavia D’Oria

    (PhD Course in “Translational Medicine and Oncology”, Department of Medical and Surgical Sciences and Translational Medicine, Sapienza University, 00185 Rome, Italy)

  • Giacomo Corrado

    (Dipartimento Scienze della Salute della Donna, del Bambino, e di Sanità Pubblica, Ginecologia Oncologica, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy)

  • Antonio Simone Laganà

    (Unit of Gynecologic Oncology, ARNAS “Civico–Di Cristina–Benfratelli”, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy)

  • Vito Chiantera

    (Unit of Gynecologic Oncology, ARNAS “Civico–Di Cristina–Benfratelli”, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy)

  • Enrico Vizza

    (Gynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCSS-Regina Elena National Cancer Institute, 00144 Rome, Italy)

  • Andrea Giannini

    (PhD Course in “Translational Medicine and Oncology”, Department of Medical and Surgical Sciences and Translational Medicine, Sapienza University, 00185 Rome, Italy)

Abstract

Cervical cancer is the most common gynecologic malignancy and the fourth most common cancer in women worldwide. Over the last two decades, minimally invasive surgery (MIS) has emerged as the mainstay in the surgical management of early-stage cervical cancer, bringing advantages such as a lower operative morbidity and shorter hospital stay compared to open surgery, while maintaining comparable oncologic outcomes in numerous retrospective studies. Considering oncological patients, it is mandatory to assess the oncological outcomes and safety of this type of surgery. Moreover, there are different future outlooks on cervical cancer therapy, based on immunotherapy, target therapy, and poly-ADP-ribose polymerases (PARP) inhibitors in combination with each other, and in combination with standard chemotherapy and radiotherapy. The goal is to find an approach that is as personalized as possible.

Suggested Citation

  • Ottavia D’Oria & Giacomo Corrado & Antonio Simone Laganà & Vito Chiantera & Enrico Vizza & Andrea Giannini, 2022. "New Advances in Cervical Cancer: From Bench to Bedside," IJERPH, MDPI, vol. 19(12), pages 1-5, June.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:12:p:7094-:d:835175
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    Citations

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    Cited by:

    1. Basilio Pecorino & Maria Gabriella D’Agate & Giuseppe Scibilia & Paolo Scollo & Andrea Giannini & Mariano Catello Di Donna & Vito Chiantera & Antonio Simone Laganà, 2022. "Evaluation of Surgical Outcomes of Abdominal Radical Hysterectomy and Total Laparoscopic Radical Hysterectomy for Cervical Cancer: A Retrospective Analysis of Data Collected before the LACC Trial," IJERPH, MDPI, vol. 19(20), pages 1-9, October.
    2. Meagan Whitney & Silvia Chávez-Baray & Alicia Villarreal & Eva Moya, 2023. "Cervical Cancer Prevention and Treatment Needs among Hispanic Women Living on the US-Mexico Border," SAGE Open, , vol. 13(4), pages 21582440231, December.

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