IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i11p6368-d822630.html
   My bibliography  Save this article

Relationship between Exercise Intensity and IL-6 Increase during an 80 km Long-Distance Running Race

Author

Listed:
  • Romain Jouffroy

    (Intensive Care Unit, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), 92100 Boulogne-Billancourt, France
    IRMES—Institute for Research in Medicine and Epidemiology of Sport, INSEP, 75012 Paris, France
    INSERM U-1018, Centre de Recherche en Epidémiologie et Santé des Populations, Paris Saclay University, 94800 Paris, France
    URP 7329, Université de Paris, 75012 Paris, France)

  • Dany Anglicheau

    (Necker-Enfants Malades Institute, French National Institute of Health and Medical Research U1151, 75015 Paris, France
    Paris Descartes, Sorbonne Paris Cité University, 75006 Paris, France
    Department of Nephrology and Kidney Transplantation, Necker Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), 75015 Paris, France)

  • Nicolas Mansencal

    (INSERM U-1018, Centre de Recherche en Epidémiologie et Santé des Populations, Paris Saclay University, 94800 Paris, France
    Department of Cardiology, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de Référence des Cardiomyopathies et des Troubles du Rythme Cardiaque Héréditaires Ou Rares, Université de Versailles-Saint Quentin (UVSQ), 92100 Boulogne, France)

  • Jean François Toussaint

    (IRMES—Institute for Research in Medicine and Epidemiology of Sport, INSEP, 75012 Paris, France
    URP 7329, Université de Paris, 75012 Paris, France
    Centre d’Investigations en Médecine du Sport, Hôtel-Dieu, Assistance Publique-Hôpitaux de Paris (AP-HP), 75004 Paris, France)

  • Juliana Antero

    (IRMES—Institute for Research in Medicine and Epidemiology of Sport, INSEP, 75012 Paris, France)

Abstract

Background : IL-6 plasma concentration (IL-6PC) reflects the systemic inflammation related to exercise intensity level. This study aims to describe the IL-6PC kinetics during a long-distance running race. IL-6PC was measured in 20 male runners before (0 km), at each refreshment point (at 21 and 53 km, i.e., k 21 and k 53 , respectively) and at the end of an 80 km long-distance run (k 80 ). Methods : IL-6PC variations (absolute and relative values in each of the three sections (S)) were calculated over S1 (0_k 21 ), S2 (k 21 _k 53 ) and S3 (k 53 _k 80 ) and compared with the exercise intensity (duration*race speed) within each section. Results : The mean IL-6PC increased during the run: 2.1 ± 0.6 ng.L −1 at 0 km, 21.0 ± 11.3 ng.L −1 at k 21 , 38.9 ± 13.0 ng.L −1 at k 53 and 49.8 ± 11.9 ng.L −1 at k 80 . Exercise intensity increased between S1 (24.2 ± 0.5) and S2 (51.9 ± 3.2) ( p = 0.04) but not between S2 and S3 (67.4 ± 4.5) ( p = 0.69). IL-6PC variation was associated with exercise intensity within S1 ( p = 0.03) and S2 ( p = 2 × 10 −3 ) and showed at least a trend within S3 ( p = 0.06). Conclusions : IL-6PC increases that occur during the early stages of a long-distance run are associated with the running intensity, and then IL-6PC remain stable after the reduction in intensity related to the decrease in running speed.

Suggested Citation

  • Romain Jouffroy & Dany Anglicheau & Nicolas Mansencal & Jean François Toussaint & Juliana Antero, 2022. "Relationship between Exercise Intensity and IL-6 Increase during an 80 km Long-Distance Running Race," IJERPH, MDPI, vol. 19(11), pages 1-7, May.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:11:p:6368-:d:822630
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/11/6368/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/11/6368/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Juliana Antero-Jacquemin & François Deni Desgorces & Frédéric Dor & Adrien Sedeaud & Amal Haïda & Philippe LeVan & Jean-François Toussaint, 2014. "Row for Your Life: A Century of Mortality Follow-Up of French Olympic Rowers," PLOS ONE, Public Library of Science, vol. 9(11), pages 1-5, November.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Kalwij, Adriaan, 2018. "The effects of competition outcomes on health: Evidence from the lifespans of U.S. Olympic medalists," Economics & Human Biology, Elsevier, vol. 31(C), pages 276-286.
    2. Romain Jouffroy & Oussama Benaceur & Jean-François Toussaint & Juliana Antero, 2022. "Echocardiographic Assessment of Left Ventricular Function 10 Years after the Ultra-Endurance Running Event Eco-Trail de Paris ® 2011," IJERPH, MDPI, vol. 19(14), pages 1-9, July.
    3. Adriaan Kalwij, 2019. "The socio-economic status gradient in median lifespan by birth cohorts: Evidence from Dutch Olympic athletes born between 1852 and 1947," PLOS ONE, Public Library of Science, vol. 14(12), pages 1-11, December.

    More about this item

    Keywords

    ;
    ;
    ;
    ;
    ;

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:11:p:6368-:d:822630. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.