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Symptom Profiles, Health-Related Quality of Life, and Clinical Blood Markers among Korean Community-Dwelling Older Adults Living with Chronic Conditions

Author

Listed:
  • Jongmin Park

    (College of Nursing, Pusan National University, Gyeongsangnam-do 50612, Korea)

  • Nada Lukkahatai

    (School of Nursing, Johns Hopkins University, Baltimore, MD 21218, USA)

  • Nancy Perrin

    (School of Nursing, Johns Hopkins University, Baltimore, MD 21218, USA)

  • Yoonju Kim

    (Department of Nursing, Graduate School, Kyung Hee University, Seoul 02447, Korea)

  • Leorey N. Saligan

    (National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, USA)

  • Chang Won Won

    (Elderly Frailty Research Center, Department of Family Medicine, College of Medicine, Kyung Hee University, Seoul 02447, Korea)

Abstract

Older adults suffer from multiple symptoms, which negatively affects their health-related quality of life. The single-symptom management approach has been less than effective. The data of 2362 Korean community-dwelling older adults aged 70 and above were analyzed in the Korean Frailty and Aging Cohort Study (KFACS) study. A cluster analysis, correlation analysis, and logistic regression were used to analyze the data. We found three symptom clusters: high symptom burden (HSB, n = 1032); pain and fatigue group (PAF, n = 566); and the sleep deprivation group (SDP, n = 764). Participants in the HSB group are more likely to be of old age (OR = 1.1), be female (OR = 2.4), live in a rural area (OR = 1.4), have low physical activity (OR = 0.9), and have multiple chronic conditions (OR = 1.5). The clinical blood markers analysis showed a negative relationship among the physical health, free T4 ( r = −0.083, p < 0.01) and insulin ( r = −0.084, p < 0.01). The sex-specific blood markers analysis showed differences among three clusters. While free testosterone (male: r = 0.124, female: r = 0.110, p < 0.05) and dehydroepiandrosterone (DHEA) (male: r = 0.352 and female: r = 0.134, p < 0.05) were associated with physical health in the HSB group, only free testosterone was associated with mental health (male: r = −0.093, and female: r = −0.116, p < 0.05) in the SDP group. These findings suggest the potential role of the patient’s sex and sex hormones in symptoms of Korean community-dwelling older adults. Understanding the symptom profiles and impact of biopsychosocial factors may enhance precision symptom management.

Suggested Citation

  • Jongmin Park & Nada Lukkahatai & Nancy Perrin & Yoonju Kim & Leorey N. Saligan & Chang Won Won, 2021. "Symptom Profiles, Health-Related Quality of Life, and Clinical Blood Markers among Korean Community-Dwelling Older Adults Living with Chronic Conditions," IJERPH, MDPI, vol. 18(4), pages 1-12, February.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:4:p:1745-:d:497556
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    References listed on IDEAS

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    1. Youn-Jung Son & Kyounghoon Lee & Bo-Hwan Kim, 2019. "Gender Differences in the Association between Frailty, Cognitive Impairment, and Self-Care Behaviors Among Older Adults with Atrial Fibrillation," IJERPH, MDPI, vol. 16(13), pages 1-12, July.
    2. Kyungwon Choi & Gyeong-Suk Jeon & Kwang-Sim Jang, 2020. "Gender Differences in the Impact of Intergenerational Support on Depressive Symptoms among Older Adults in Korea," IJERPH, MDPI, vol. 17(12), pages 1-13, June.
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