IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i20p10997-d660047.html
   My bibliography  Save this article

Adult-Attention Deficit Hyperactive Disorder Symptoms Seem Not to Influence the Outcome of an Enhanced Agonist Opioid Treatment: A 30-Year Follow-Up

Author

Listed:
  • Angelo G. I. Maremmani

    (North-Western Tuscany Local Health Unit, Department of Psychiatry, Tuscany NHS, Versilia Zone, 55049 Viareggio, Italy
    Association for the Application of Neuroscientific Knowledge to Social Aims (AU-CNS), 55045 Pietrasanta, Italy
    PISA-School of Experimental and Clinical Psychiatry, 56100 Pisa, Italy)

  • Pasqualina Rocco

    (Drug Addiction Unit, 31033 Castelfranco Veneto, Italy)

  • Filippo Della Rocca

    (School of Psychiatry, Department of Clinical and Experimental Psychiatry, University of Pisa, 56100 Pisa, Italy)

  • Giulio Perugi

    (VP Dole Dual Disorder Research Group, 2nd Psychiatric Unit, Department of Clinical and Experimental Psychiatry, University of Pisa, 56100 Pisa, Italy)

  • Mario Miccoli

    (Department of Clinical and Experimental Medicine, University of Pisa, 56100 Pisa, Italy)

  • Icro Maremmani

    (Association for the Application of Neuroscientific Knowledge to Social Aims (AU-CNS), 55045 Pietrasanta, Italy
    Saint Camillus International University of Health and Medical Sciences—UniCamillus, 00131 Rome, Italy
    G. De Lisio Institute of Behavioural Sciences, 56100 Pisa, Italy)

Abstract

The role of opioids and opioid medications in ADHD symptoms is still largely understudied. We tested the hypothesis that, in Heroin Use Disorder (HUD), when patients are treated with Agonist Opioid medications (AOT), treatment outcome is associated with the presence of Adult Attention-Deficit/Hyperactive Disorder (A-ADHD) symptomatology. A retrospective cohort study of 130 HUD patients in Castelfranco Veneto, Italy, covering 30 years, was divided into two groups according to the Adult ADHD Self-Report Scale (ASRS) score and compared them using demographic, clinical and pharmacological factors. Survival in treatment was studied by utilizing the available data for leaving treatment and relapsing into addictive behavior and for mortality during treatment as poor primary outcomes. Thirty-five HUD subjects (26.9%) were unlikely to have A-ADHD symptomatology, and 95 (73.1%) were likely to have it. Only current age and co-substance use at treatment entry differed significantly between groups. Censored patients were 29 (82.9%) for HUD patients and 70 (73.9%) for A-ADHD/HUD patients (Mantel-Cox test = 0.66 p = 0.415). There were no significant linear trends indicative of a poorer outcome with the presence of A-ADHD after adjustment for demographic, clinical and pharmacological factors. Conclusions: ADHD symptomatology does not seem to exert any influence on the retention in AOT of HUD patients.

Suggested Citation

  • Angelo G. I. Maremmani & Pasqualina Rocco & Filippo Della Rocca & Giulio Perugi & Mario Miccoli & Icro Maremmani, 2021. "Adult-Attention Deficit Hyperactive Disorder Symptoms Seem Not to Influence the Outcome of an Enhanced Agonist Opioid Treatment: A 30-Year Follow-Up," IJERPH, MDPI, vol. 18(20), pages 1-13, October.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:20:p:10997-:d:660047
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/20/10997/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/18/20/10997/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Vincenza Spera & Alessandro Pallucchini & Marco Maiello & Marco Carli & Angelo G. I. Maremmani & Giulio Perugi & Icro Maremmani, 2020. "Substance Use Disorder in Adult-Attention Deficit Hyperactive Disorder Patients: Patterns of Use and Related Clinical Features," IJERPH, MDPI, vol. 17(10), pages 1-11, May.
    2. Corrado Manni & Giada Cipollone & Alessandro Pallucchini & Angelo G. I. Maremmani & Giulio Perugi & Icro Maremmani, 2019. "Remarkable Reduction of Cocaine Use in Dual Disorder (Adult Attention Deficit Hyperactive Disorder/Cocaine Use Disorder) Patients Treated with Medications for ADHD," IJERPH, MDPI, vol. 16(20), pages 1-12, October.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Alessandro Pallucchini & Marco Carli & Marco Scarselli & Icro Maremmani & Giulio Perugi, 2021. "Symptomatological Variants and Related Clinical Features in Adult Attention Deficit Hyperactive Disorder," IJERPH, MDPI, vol. 18(3), pages 1-13, January.
    2. Vincenza Spera & Alessandro Pallucchini & Marco Maiello & Marco Carli & Angelo G. I. Maremmani & Giulio Perugi & Icro Maremmani, 2020. "Substance Use Disorder in Adult-Attention Deficit Hyperactive Disorder Patients: Patterns of Use and Related Clinical Features," IJERPH, MDPI, vol. 17(10), pages 1-11, May.
    3. Anders Dahlen Forsmo Lauvsnes & Mette Langaas & Alexander Olsen & Jasmin Vassileva & Olav Spigset & Rolf W. Gråwe, 2021. "ADHD and Mental Health Symptoms in the Identification of Young Adults with Increased Risk of Alcohol Dependency in the General Population—The HUNT4 Population Study," IJERPH, MDPI, vol. 18(21), pages 1-11, November.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:20:p:10997-:d:660047. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.